Gene Details:

• Gene ID: Csa1M085890
• Gene Symbol: CsaMLO1
• Gene Name: Mildew Locus O1
• Genome:
• Species: Cucumis sativus

Functional Descriptions:

• CsaMLO1 and CsaMLO11 were cloned from cucumber and overexpressed in a tomato mlo mutant.
• Heterologous overexpression of all three CsaMLO genes in the tomato mlo mutant restored susceptibility to PM caused by Oidium neolycopersici, albeit to a different extent: whereas overexpression of CsaMLO1 or CsaMLO8 completely restored susceptibility, overexpression of CsaMLO11 was only partially able to restore PM susceptibility.
• Both CsaMLO1 and CsaMLO11 are functional susceptibility genes, although we conclude that based on the transcript abundance CsaMLO8 is probably the major clade V MLO gene in cucumber regarding providing susceptibility to PM.
• Potential loss-of-function mutations in CsaMLO1 and CsaMLO11 have not been identified. The generation and analysis of such mutants are interesting subjects for further investigation.

Function-related keywords:

Literature:

• Functional characterization of cucumber (Cucumis sativus L.) Clade V MLO genes.   DOI:  10.1186/s12870-017-1029-z ;  PMID:  28431513

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions:

Orthologs:

Sequences:

• CDS Sequence:
• Protein Sequence: