Gene Details:

• Gene ID: AT2G43800
• Gene Symbol: FH2, FH2
• Gene Name: Formin 2, formin homology 2
• Description: Actin-binding FH2 (formin homology 2) family protein;(source:Araport11)
• TAIR Accession: locus:2043989
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT2G43800.1

Plant Ontology Annotations:

• PO:0000037  — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
• PO:0008019  — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0009006  — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
• PO:0009009  — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
• PO:0009025  — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
• PO:0009029  — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
• PO:0009031  — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
• PO:0009052  — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
• PO:0020030  — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
• PO:0020038  — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
• PO:0020100  — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
• PO:0020137  — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
• PO:0025022  — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)

Gene Ontology:

• GO:0045010  — involved in — actin nucleation
• GO:0051015  — enables — actin filament binding
• GO:0010497  — acts upstream of or within — plasmodesmata-mediated intercellular transport
• GO:0051016  — acts upstream of or within — barbed-end actin filament capping
• GO:0003779  — enables — actin binding
• GO:0009506  — colocalizes with — plasmodesma

Germplasm Phenotype:

• atfh1 atfh2  — Increased plasmodesmata permeability.
• atfh2-1  — Plasmodesmata permeability and sensitivity to virus infection are increased; inhibited leave growth.
• atfh2-2  — Plasmodesmata permeability and sensitivity to virus infection are increased; inhibited leave growth.

Function-related keywords:

• shoot axis apex ,  leaf lamina base ,  root ,  shoot system ,  plant embryo ,  vascular leaf ,  stamen ,  sepal ,  flower ,  inflorescence flower pedicel ,  cotyledon ,  petiole ,  hypocotyl ,  leaf apex ,  collective leaf structure

Literature:

• Formins: intermediates in signal-transduction cascades that affect cytoskeletal reorganization.   DOI:  10.1016/s1360-1385(02)02341-5 ;  PMID:  12417149
• Formin homology 2 domains occur in multiple contexts in angiosperms.   DOI:  10.1186/1471-2164-5-44 ;  PMID:  15256004
• Functional compensation of primary and secondary metabolites by duplicate genes in Arabidopsis thaliana.   DOI:  10.1093/molbev/msq204 ;  PMID:  20736450
• Endogenous Arabidopsis messenger RNAs transported to distant tissues.   DOI:  10.1038/nplants.2015.25 ;  PMID:  27247031
• Arabidopsis formin 2 regulates cell-to-cell trafficking by capping and stabilizing actin filaments at plasmodesmata.   DOI:  10.7554/eLife.36316 ;  PMID:  30113309
• SH3Ps-Evolution and Diversity of a Family of Proteins Engaged in Plant Cytokinesis.   DOI:  10.3390/ijms20225623 ;  PMID:  31717902
• AtFH14 crosslinks actin filaments and microtubules in different manners.   DOI:  10.1111/boc.202000147 ;  PMID:  33386758
• Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.   DOI:  10.1074/mcp.M600429-MCP200 ;  PMID:  17317660

Sequence: