Gene Details:

• Gene ID: AT3G03940
• Gene Symbol: AEL3, MLK2, PPK3
• Gene Name: Arabidopsis EL1-like 3, MUT9P-LIKE-KINASE 2, Photoregulatory Protein Kinase 3
• Description: Protein kinase family protein;(source:Araport11)
• TAIR Accession: locus:2079329
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT3G03940.1

Gene Ontology:

• GO:0007165  — involved in — signal transduction
• GO:0006468  — acts upstream of or within — protein phosphorylation
• GO:0005634  — located in — nucleus
• GO:0018105  — involved in — peptidyl-serine phosphorylation
• GO:0004672  — enables — protein kinase activity
• GO:0004674  — enables — protein serine/threonine kinase activity
• GO:0001932  — acts upstream of or within — regulation of protein phosphorylation
• GO:0009788  — acts upstream of or within — negative regulation of abscisic acid-activated signaling pathway
• GO:0009740  — acts upstream of or within — gibberellic acid mediated signaling pathway
• GO:0003677  — enables — DNA binding
• GO:0005515  — enables — protein binding
• GO:0005634  — is active in — nucleus
• GO:0006897  — involved in — endocytosis
• GO:0005737  — is active in — cytoplasm

Germplasm Phenotype:

• CS71657  — Reduced seed production.
• CS71658  — Reduced light-induced degradation of phyB. Short hypocotyl in continuous red light (Rc). Reduced seed production.
• CS71747  — Reduced light-induced PIF3 phosphorylation and degradation; light-induced phyB degradation also strongly reduced. Hypersensitive to red light; short hypocotyl and enhanced cotyledon expansion in continuous R light. Very small seed set, short siliques (unpublished observations).
• CS71748  — Red-light hypersensitive phenotype of the ppk123 triple mutant (CS71747) is strongly suppressed in the phyB mutant background. Long hypocotyl in continuous R light, open cotyledons. Very small seed set (non-published observation).
• ael123  — hypersensitive response to ABA, reduced seed germination ratio or green cotyledon percentage, suppressed lateral root elongation under ABA treatment, reduced stomatal aperture under ABA treatment, reduced germination under salinity
• ael134  — hypersensitive response to ABA, reduced seed germination ratio or green cotyledon percentage, suppressed lateral root elongation under ABA treatment, reduced stomatal aperture under ABA treatment, reduced germination under salinity
• mlk2-3  — Short hypocotyls,sensitive to pacloburazol.

Literature:

• Autophosphorylation profiling of Arabidopsis protein kinases using the cell-free system.   DOI:  10.1016/j.phytochem.2011.02.029 ;  PMID:  21477822
• Osmotic stress induces phosphorylation of histone H3 at threonine 3 in pericentromeric regions of Arabidopsis thaliana.   DOI:  10.1073/pnas.1423325112 ;  PMID:  26100864
• Molecular basis for blue light-dependent phosphorylation of Arabidopsis cryptochrome 2.   DOI:  10.1038/ncomms15234 ;  PMID:  28492234
• Phosphorylation of Histone H2A at Serine 95: A Plant-Specific Mark Involved in Flowering Time Regulation and H2A.Z Deposition.   DOI:  10.1105/tpc.17.00266 ;  PMID:  28790150
• MLK1 and MLK2 Coordinate RGA and CCA1 Activity to Regulate Hypocotyl Elongation in Arabidopsis thaliana.   DOI:  10.1105/tpc.17.00830 ;  PMID:  29255112
• Comparative Analysis of CDPK Family in Maize, Arabidopsis, Rice, and Sorghum Revealed Potential Targets for Drought Tolerance Improvement.   DOI:  10.3389/fchem.2017.00115 ;  PMID:  29312925
• EL1-like Casein Kinases Suppress ABA Signaling and Responses by Phosphorylating and Destabilizing the ABA Receptors PYR/PYLs in Arabidopsis.   DOI:  10.1016/j.molp.2018.02.012 ;  PMID:  29505832
• PPKs mediate direct signal transfer from phytochrome photoreceptors to transcription factor PIF3.   DOI:  10.1038/ncomms15236 ;  PMID:  28492231
• Comparative Analysis of CDPK Family in Maize, Arabidopsis, Rice, and Sorghum Revealed Potential Targets for Drought Tolerance Improvement.   DOI:  10.3389/fchem.2017.00115 ;  PMID:  29312925

Sequence: