Gene Details:

• Gene ID: AT3G08530
• Gene Symbol: AtCHC2, CHC2
• Gene Name: clathrin heavy chain 2
• Description: Clathrin, heavy chain;(source:Araport11)
• TAIR Accession: locus:2103442
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT3G08530.1

Gene Ontology:

• GO:0016192  — acts upstream of or within — vesicle-mediated transport
• GO:0042802  — enables — identical protein binding
• GO:0006886  — involved in — intracellular protein transport
• GO:0009506  — located in — plasmodesma
• GO:0009507  — located in — chloroplast
• GO:0005515  — enables — protein binding
• GO:0006898  — involved in — receptor-mediated endocytosis
• GO:0005886  — located in — plasma membrane
• GO:0005198  — enables — structural molecule activity
• GO:0030130  — part of — clathrin coat of trans-Golgi network vesicle
• GO:0005794  — located in — Golgi apparatus
• GO:0030132  — part of — clathrin coat of coated pit
• GO:0032051  — enables — clathrin light chain binding
• GO:0071439  — part of — clathrin complex
• GO:0006897  — acts upstream of or within — endocytosis
• GO:0003729  — enables — mRNA binding

Germplasm Phenotype:

• SALK_028826  — Homozygous mutants have increased tolerance to water stress and reduced rate of exocytosis.
• SALK_151638  — Homozygous mutants have increased tolerance to water stress and reduced rate of exocytosis.

Literature:

• A chloroplast-localized vesicular transport system: a bio-informatics approach.   DOI:  10.1186/1471-2164-5-40 ;  PMID:  15236667
• Autophosphorylation profiling of Arabidopsis protein kinases using the cell-free system.   DOI:  10.1016/j.phytochem.2011.02.029 ;  PMID:  21477822
• Identification of novel candidate phosphatidic acid-binding proteins involved in the salt-stress response of Arabidopsis thaliana roots.   DOI:  10.1042/BJ20121639 ;  PMID:  23323832
• The TPLATE adaptor complex drives clathrin-mediated endocytosis in plants.   DOI:  10.1016/j.cell.2014.01.039 ;  PMID:  24529374
• ENHANCED DISEASE RESISTANCE4 associates with CLATHRIN HEAVY CHAIN2 and modulates plant immunity by regulating relocation of EDR1 in Arabidopsis.   DOI:  10.1105/tpc.114.134668 ;  PMID:  25747881
• A Functional Study of AUXILIN-LIKE1 and 2, Two Putative Clathrin Uncoating Factors in Arabidopsis.   DOI:  10.1105/tpc.17.00785 ;  PMID:  29511054
• The Inhibitor Endosidin 4 Targets SEC7 Domain-Type ARF GTPase Exchange Factors and Interferes with Subcellular Trafficking in Eukaryotes.   DOI:  10.1105/tpc.18.00127 ;  PMID:  30018156
• RECEPTOR-LIKE KINASE 902 Associates with and Phosphorylates BRASSINOSTEROID-SIGNALING KINASE1 to Regulate Plant Immunity.   DOI:  10.1016/j.molp.2018.10.008 ;  PMID:  30408577
• Discovering the RNA-Binding Proteome of Plant Leaves with an Improved RNA Interactome Capture Method.   DOI:  10.3390/biom10040661 ;  PMID:  32344669
• SINAT E3 Ubiquitin Ligases Mediate FREE1 and VPS23A Degradation to Modulate Abscisic Acid Signaling.   DOI:  10.1105/tpc.20.00267 ;  PMID:  32753431
• The Arabidopsis thaliana chloroplast proteome reveals pathway abundance and novel protein functions.   DOI:  10.1016/j.cub.2004.02.039 ;  PMID:  15028209
• Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.   DOI:  10.1074/mcp.M600429-MCP200 ;  PMID:  17317660
• Membrane proteomic analysis of Arabidopsis thaliana using alternative solubilization techniques.   DOI:  10.1021/pr060525b ;  PMID:  17432890
• Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.   DOI:  10.1371/journal.pone.0001994 ;  PMID:  18431481
• Analysis of protein complexes in Arabidopsis leaves using size exclusion chromatography and label-free protein correlation profiling.   DOI:  10.1016/j.jprot.2017.06.004 ;  PMID:  28627464

Sequence: