Gene Details:

• Gene ID: AT3G12990
• Gene Symbol: RRP45a
• Gene Name: ribonuclease PH45A
• Description: ribonuclease PH45A;(source:Araport11)
• TAIR Accession: locus:2089215
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT3G12990.1     AT3G12990.2     AT3G12990.3     AT3G12990.4

Gene Ontology:

• GO:0000176  — part of — nuclear exosome (RNase complex)
• GO:0071042  — involved in — nuclear polyadenylation-dependent mRNA catabolic process
• GO:0043928  — involved in — exonucleolytic catabolism of deadenylated mRNA
• GO:0034475  — involved in — exonucleolytic trimming to generate mature 3-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
• GO:0000177  — part of — cytoplasmic exosome (RNase complex)
• GO:0005737  — located in — cytoplasm
• GO:0071035  — involved in — nuclear polyadenylation-dependent rRNA catabolic process
• GO:0071028  — involved in — nuclear mRNA surveillance
• GO:0000175  — enables — 3-5-RNA exonuclease activity
• GO:0034473  — involved in — U1 snRNA 3-end processing
• GO:0071038  — involved in — nuclear polyadenylation-dependent tRNA catabolic process
• GO:0000967  — involved in — U5 snRNA 3-end processing

Germplasm Phenotype:

• cer7-3 Atrrp45a  — The double mutant is gametophytic lethal for both female and male gametophytes.

Literature:

• Genome-based analysis of Chlamydomonas reinhardtii exoribonucleases and poly(A) polymerases predicts unexpected organellar and exosomal features.   DOI:  10.1534/genetics.107.086223 ;  PMID:  18493045

Sequence: