Gene Details:

• Gene ID: AT3G43210
• Gene Symbol: ATNACK2, NACK2, TES
• Gene Name: ARABIDOPSIS NPK1-ACTIVATING KINESIN 2, NPK1-ACTIVATING KINESIN 2, TETRASPORE
• Description: ATP binding microtubule motor family protein;(source:Araport11)
• TAIR Accession: locus:2084701
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT3G43210.1     AT3G43210.3     AT3G43210.2     AT3G43210.4     AT3G43210.5

Plant Ontology Annotations:

• PO:0000037  — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0009009  — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
• PO:0009025  — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
• PO:0009029  — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
• PO:0009031  — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
• PO:0009052  — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
• PO:0020100  — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
• PO:0025022  — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
• PO:0025281  — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)

Gene Ontology:

• GO:0008017  — enables — microtubule binding
• GO:0007112  — acts upstream of or within — male meiosis cytokinesis
• GO:0009558  — acts upstream of or within — embryo sac cellularization
• GO:0009506  — located in — plasmodesma
• GO:0010245  — acts upstream of or within — radial microtubular system formation
• GO:0000911  — acts upstream of or within — cytokinesis by cell plate formation
• GO:0007018  — involved in — microtubule-based movement
• GO:0048229  — acts upstream of or within — gametophyte development
• GO:0005634  — located in — nucleus
• GO:0009555  — acts upstream of or within — pollen development
• GO:0003777  — enables — microtubule motor activity

Germplasm Phenotype:

• CS9353  — Partial cytokninesis; failure of cytokinesis at the end of male meiosis; large pollen grains with extra apertures in abnormal orientation; variable numbers of extra nuclei in pollen; pollen tubes may transmit multiple pairs of sperm; many sperm are polyploid; reduced male fertility, partly due to seed abortion (NB female fertility is normal); many of the viable embryos are polyploid.

Function-related keywords:

• shoot axis apex ,  root ,  plant embryo ,  vascular leaf ,  stamen ,  sepal ,  flower ,  inflorescence flower pedicel ,  hypocotyl ,  collective leaf structure ,  pollen

Literature:

• The AtNACK1/HINKEL and STUD/TETRASPORE/AtNACK2 genes, which encode functionally redundant kinesins, are essential for cytokinesis in Arabidopsis.   DOI:  10.1111/j.1365-2443.2004.00798.x ;  PMID:  15569152
• Arabidopsis kinesins HINKEL and TETRASPORE act redundantly to control cell plate expansion during cytokinesis in the male gametophyte.   DOI:  10.1093/mp/ssn042 ;  PMID:  19825582
• HINKEL kinesin, ANP MAPKKKs and MKK6/ANQ MAPKK, which phosphorylates and activates MPK4 MAPK, constitute a pathway that is required for cytokinesis in Arabidopsis thaliana.   DOI:  10.1093/pcp/pcq135 ;  PMID:  20802223
• NACK kinesin is required for metaphase chromosome alignment and cytokinesis in the moss Physcomitrella patens.   DOI:  10.1247/csf.14016 ;  PMID:  25748359
• Arabidopsis Fused kinase TWO-IN-ONE dominantly inhibits male meiotic cytokinesis.   DOI:  10.1007/s00497-013-0235-6 ;  PMID:  24146312
• Mitosis-specific kinesins in Arabidopsis.   DOI:  10.1016/j.tplants.2006.02.004 ;  PMID:  16530461

Sequence: