Gene Details:

• Gene ID: AT3G46580
• Gene Symbol: ATMBD5, MBD05, MBD5
• Gene Name: METHYL-CPG-BINDING DOMAIN PROTEIN 05, methyl-CPG-binding domain protein 5
• Description: methyl-CPG-binding domain protein 5;(source:Araport11)
• TAIR Accession: locus:2075135
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT3G46580.1

Plant Ontology Annotations:

• PO:0000037  — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
• PO:0008019  — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0009006  — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
• PO:0009009  — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
• PO:0009025  — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
• PO:0009029  — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
• PO:0009031  — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
• PO:0009052  — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
• PO:0020030  — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
• PO:0020038  — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
• PO:0020100  — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
• PO:0020137  — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
• PO:0025022  — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)

Gene Ontology:

• GO:0008327  — enables — methyl-CpG binding
• GO:0010370  — located in — perinucleolar chromocenter
• GO:0005634  — located in — nucleus
• GO:0006996  — acts upstream of or within — organelle organization
• GO:0043621  — enables — protein self-association
• GO:0051052  — acts upstream of or within — regulation of DNA metabolic process
• GO:0010605  — acts upstream of or within — negative regulation of macromolecule metabolic process
• GO:0019219  — acts upstream of or within — regulation of nucleobase-containing compound metabolic process
• GO:0005515  — enables — protein binding
• GO:0000792  — part of — heterochromatin
• GO:0019899  — enables — enzyme binding

Function-related keywords:

• shoot axis apex ,  leaf lamina base ,  root ,  shoot system ,  plant embryo ,  vascular leaf ,  stamen ,  sepal ,  flower ,  inflorescence flower pedicel ,  cotyledon ,  petiole ,  hypocotyl ,  leaf apex ,  collective leaf structure

Literature:

• Characterization of Arabidopsis thaliana methyl-CpG-binding domain (MBD) proteins.   DOI:  10.1046/j.1365-313x.2003.01756.x ;  PMID:  12787239
• Ten members of the Arabidopsis gene family encoding methyl-CpG-binding domain proteins are transcriptionally active and at least one, AtMBD11, is crucial for normal development.   DOI:  10.1093/nar/gkg735 ;  PMID:  12954765
• Methylated DNA-binding proteins from Arabidopsis.   DOI:  10.1104/pp.103.026708 ;  PMID:  14605234
• Evolutionary divergence of monocot and dicot methyl-CpG-binding domain proteins.   DOI:  10.1104/pp.105.060566 ;  PMID:  15888682
• Methyl-CpG-binding domain proteins in plants: interpreters of DNA methylation.   DOI:  10.1016/j.tplants.2006.12.004 ;  PMID:  17208509
• Genetic analysis implicates a molecular chaperone complex in regulating epigenetic silencing of methylated genomic regions.   DOI:  10.1111/jipb.13155 ;  PMID:  34289245
• Single-nucleus RNA-seq reveals that MBD5, MBD6, and SILENZIO maintain silencing in the vegetative cell of developing pollen.   DOI:  10.1016/j.celrep.2022.111699 ;  PMID:  36417865

Sequence: