Gene Details:

• Gene ID: AT3G46640
• Gene Symbol: LUX, PCL1
• Gene Name: LUX ARRHYTHMO, PHYTOCLOCK 1
• Description: Homeodomain-like superfamily protein;(source:Araport11)
• TAIR Accession: locus:2075200
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT3G46640.1     AT3G46640.2     AT3G46640.3

Gene Ontology:

• GO:0003700  — enables — DNA-binding transcription factor activity
• GO:0006355  — acts upstream of or within — regulation of DNA-templated transcription
• GO:0005634  — is active in — nucleus
• GO:0005634  — located in — nucleus
• GO:0010468  — acts upstream of or within — regulation of gene expression
• GO:0042753  — involved in — positive regulation of circadian rhythm
• GO:0007623  — acts upstream of or within — circadian rhythm
• GO:0007623  — involved in — circadian rhythm

Germplasm Phenotype:

• lux-1  — Long hypocotyl. Plants flower early in short- and long-day conditions. Arrhythmic CAB2:LUC (reporter gene) expression and leaf movement in constant light, monochromatic red or blue light. Arrhythmic CCR2::LUC (reporter gene) expression in constant dark and constant light.
• lux-2  — Long hypocotyl. Plants flower early in short- and long-day conditions. Arrhythmic CAB2:LUC (reporter gene) expression and leaf movement in constant light, monochromatic red or blue light.
• lux-3  — Long hypocotyl seedlings. Arrhythmic CAB2::LUC (reporter gene) expression under constant light.
• lux-4  — Long hypocotyl seedlings. Arrhythmic CAB2::LUC (reporter gene) expression under constant light.
• lux-5  — Long hypocotyl seedlings. Arrhythmic CAB2::LUC (reporter gene) expression under constant light.

Literature:

• Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.   DOI:  10.1126/science.290.5499.2105 ;  PMID:  11118137
• LUX ARRHYTHMO encodes a Myb domain protein essential for circadian rhythms.   DOI:  10.1073/pnas.0503029102 ;  PMID:  16006522
• PHYTOCLOCK 1 encoding a novel GARP protein essential for the Arabidopsis circadian clock.   DOI:  10.1111/j.1365-2443.2005.00892.x ;  PMID:  16164597
• Comparative overviews of clock-associated genes of Arabidopsis thaliana and Oryza sativa.   DOI:  10.1093/pcp/pcl043 ;  PMID:  17132630
• LUX ARRHYTHMO encodes a nighttime repressor of circadian gene expression in the Arabidopsis core clock.   DOI:  10.1016/j.cub.2010.12.021 ;  PMID:  21236673
• BROTHER OF LUX ARRHYTHMO is a component of the Arabidopsis circadian clock.   DOI:  10.1105/tpc.111.084293 ;  PMID:  21447790
• The ELF4-ELF3-LUX complex links the circadian clock to diurnal control of hypocotyl growth.   DOI:  10.1038/nature10182 ;  PMID:  21753751
• EARLY FLOWERING4 recruitment of EARLY FLOWERING3 in the nucleus sustains the Arabidopsis circadian clock.   DOI:  10.1105/tpc.111.093807 ;  PMID:  22327739
• Diurnal dependence of growth responses to shade in Arabidopsis: role of hormone, clock, and light signaling.   DOI:  10.1093/mp/ssr122 ;  PMID:  22311777
• ELF3 recruitment to the PRR9 promoter requires other Evening Complex members in the Arabidopsis circadian clock.   DOI:  10.4161/psb.18766 ;  PMID:  22307044
• Accurate timekeeping is controlled by a cycling activator in Arabidopsis.   DOI:  10.7554/eLife.00473 ;  PMID:  23638299
• Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.   DOI:  10.1186/1471-2229-13-229 ;  PMID:  24377444
• Ambient temperature signal feeds into the circadian clock transcriptional circuitry through the EC night-time repressor in Arabidopsis thaliana.   DOI:  10.1093/pcp/pcu030 ;  PMID:  24500967
• The LNK1 night light-inducible and clock-regulated gene is induced also in response to warm-night through the circadian clock nighttime repressor in Arabidopsis thaliana.   DOI:  10.4161/psb.28505 ;  PMID:  24690904
• Light and the circadian clock mediate time-specific changes in sensitivity to UV-B stress under light/dark cycles.   DOI:  10.1093/jxb/eru339 ;  PMID:  25147271
• The EC night-time repressor plays a crucial role in modulating circadian clock transcriptional circuitry by conservatively double-checking both warm-night and night-time-light signals in a synergistic manner in Arabidopsis thaliana.   DOI:  10.1093/pcp/pcu144 ;  PMID:  25332490
• ELF3-PIF4 interaction regulates plant growth independently of the Evening Complex.   DOI:  10.1016/j.cub.2014.10.070 ;  PMID:  25557667
• Phototropins maintain robust circadian oscillation of PSII operating efficiency under blue light.   DOI:  10.1111/tpj.12947 ;  PMID:  26215041
• Endogenous Arabidopsis messenger RNAs transported to distant tissues.   DOI:  10.1038/nplants.2015.25 ;  PMID:  27247031
• Identification of Evening Complex Associated Proteins in Arabidopsis by Affinity Purification and Mass Spectrometry.   DOI:  10.1074/mcp.M115.054064 ;  PMID:  26545401
• The evening complex coordinates environmental and endogenous signals in Arabidopsis.   DOI:  10.1038/nplants.2017.87 ;  PMID:  28650433
• The HAF2 protein shapes histone acetylation levels of PRR5 and LUX loci in Arabidopsis.   DOI:  10.1007/s00425-018-2921-y ;  PMID:  29789923
• Circadian control of ORE1 by PRR9 positively regulates leaf senescence in Arabidopsis.   DOI:  10.1073/pnas.1722407115 ;  PMID:  30065116
• HOS15 Interacts with the Histone Deacetylase HDA9 and the Evening Complex to Epigenetically Regulate the Floral Activator GIGANTEA.   DOI:  10.1105/tpc.18.00721 ;  PMID:  30606777
• Arabidopsis JMJD5/JMJ30 Acts Independently of LUX ARRHYTHMO Within the Plant Circadian Clock to Enable Temperature Compensation.   DOI:  10.3389/fpls.2019.00057 ;  PMID:  30774641
• LUX ARRHYTHMO mediates crosstalk between the circadian clock and defense in Arabidopsis.   DOI:  10.1038/s41467-019-10485-6 ;  PMID:  31186426
• Molecular mechanisms of Evening Complex activity in Arabidopsis.   DOI:  10.1073/pnas.1920972117 ;  PMID:  32165537
• The evening complex is central to the difference between the circadian clocks of Arabidopsis thaliana shoots and roots.   DOI:  10.1111/ppl.13108 ;  PMID:  32303120
• A prion-like domain in ELF3 functions as a thermosensor in Arabidopsis.   DOI:  10.1038/s41586-020-2644-7 ;  PMID:  32848244
• The Evening Complex and the Chromatin-Remodeling Factor PICKLE Coordinately Control Seed Dormancy by Directly Repressing DOG1 in Arabidopsis.   DOI:  10.1016/j.xplc.2019.100011 ;  PMID:  33404551
• Molecular and functional dissection of EARLY-FLOWERING 3 (ELF3) and ELF4 in Arabidopsis.   DOI:  10.1016/j.plantsci.2020.110786 ;  PMID:  33487361
• Circadian Clock in Arabidopsis thaliana Determines Flower Opening Time Early in the Morning and Dominantly Closes Early in the Afternoon.   DOI:  10.1093/pcp/pcab048 ;  PMID:  33822207
• Firefly Luciferase Complementation-Based Analysis of Dynamic Protein-Protein Interactions Under Diurnal and Circadian Conditions in Arabidopsis.   DOI:  10.1007/978-1-0716-1912-4_16 ;  PMID:  34674178
• Cellular localization of Arabidopsis EARLY FLOWERING3 is responsive to light quality.   DOI:  10.1093/plphys/kiac072 ;  PMID:  35191492
• Sulfanilamide Regulates Flowering Time through Expression of the Circadian Clock Gene LUX.   DOI:  10.1093/pcp/pcac027 ;  PMID:  35238923
• REVEILLE 7 inhibits the expression of the circadian clock gene EARLY FLOWERING 4 to fine-tune hypocotyl growth in response to warm temperatures.   DOI:  10.1111/jipb.13284 ;  PMID:  35603836
• Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.   DOI:  10.1126/science.290.5499.2105 ;  PMID:  11118137
• Rapid array mapping of circadian clock and developmental mutations in Arabidopsis.   DOI:  10.1104/pp.105.061408 ;  PMID:  15908595
• Comparative overviews of clock-associated genes of Arabidopsis thaliana and Oryza sativa.   DOI:  10.1093/pcp/pcl043 ;  PMID:  17132630
• FIONA1 is essential for regulating period length in the Arabidopsis circadian clock.   DOI:  10.1105/tpc.107.055715 ;  PMID:  18281507

Sequence: