Gene Details:

• Gene ID: AT4G16340
• Gene Symbol: SPK1
• Gene Name: SPIKE1
• Description: guanyl-nucleotide exchange factors;(source:Araport11)
• TAIR Accession: locus:2130484
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT4G16340.1     AT4G16340.2

Plant Ontology Annotations:

• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)

Gene Ontology:

• GO:0005515  — enables — protein binding
• GO:0051211  — acts upstream of or within negative effect — anisotropic cell growth
• GO:0051493  — involved in — regulation of cytoskeleton organization
• GO:0016192  — acts upstream of or within — vesicle-mediated transport
• GO:0010928  — involved in — regulation of auxin mediated signaling pathway
• GO:0043622  — acts upstream of or within — cortical microtubule organization
• GO:0070971  — located in — endoplasmic reticulum exit site
• GO:0005634  — located in — nucleus
• GO:0048446  — acts upstream of or within — petal morphogenesis
• GO:0008064  — involved in — regulation of actin polymerization or depolymerization
• GO:0005085  — enables — guanyl-nucleotide exchange factor activity
• GO:0008360  — involved in — regulation of cell shape
• GO:0009958  — involved in — positive gravitropism
• GO:0043547  — involved in — positive regulation of GTPase activity
• GO:0005783  — colocalizes with — endoplasmic reticulum
• GO:0007264  — involved in — small GTPase mediated signal transduction

Function-related keywords:

• root

Literature:

• The role of Arabidopsis SCAR genes in ARP2-ARP3-dependent cell morphogenesis.   DOI:  10.1242/dev.02792 ;  PMID:  17267444
• Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.   DOI:  10.1021/pr8000173 ;  PMID:  18433157
• Transcriptome analysis of Arabidopsis wild-type and gl3-sst sim trichomes identifies four additional genes required for trichome development.   DOI:  10.1093/mp/ssp037 ;  PMID:  19626137
• A ROP GTPase-dependent auxin signaling pathway regulates the subcellular distribution of PIN2 in Arabidopsis roots.   DOI:  10.1016/j.cub.2012.05.019 ;  PMID:  22683260
• The endoplasmic reticulum is a reservoir for WAVE/SCAR regulatory complex signaling in the Arabidopsis leaf.   DOI:  10.1104/pp.113.217422 ;  PMID:  23613272
• SPIKE1 Activates ROP GTPase to Modulate Petal Growth and Shape.   DOI:  10.1104/pp.16.00788 ;  PMID:  27440754
• Spatio-temporal orientation of microtubules controls conical cell shape in Arabidopsis thaliana petals.   DOI:  10.1371/journal.pgen.1006851 ;  PMID:  28644898
• Auxin and ROP GTPase Signaling of Polar Nuclear Migration in Root Epidermal Hair Cells.   DOI:  10.1104/pp.17.00713 ;  PMID:  29084900
• Microtubule-Dependent Confinement of a Cell Signaling and Actin Polymerization Control Module Regulates Polarized Cell Growth.   DOI:  10.1016/j.cub.2018.05.076 ;  PMID:  30033335
• A New Allele of the SPIKE1 Locus Reveals Distinct Regulation of Trichome and Pavement Cell Development and Plant Growth.   DOI:  10.3389/fpls.2019.00016 ;  PMID:  30733726
• Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.   DOI:  10.1074/mcp.M600429-MCP200 ;  PMID:  17317660
• Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.   DOI:  10.1021/pr8000173 ;  PMID:  18433157
• Analysis of the Arabidopsis cytosolic proteome highlights subcellular partitioning of central plant metabolism.   DOI:  10.1021/pr1009433 ;  PMID:  21166475

Sequence: