Gene Details:

• Gene ID: AT4G24710
• Gene Symbol: PCH2, TRIP13
• Gene Name:
• Description: pachytene checkpoint-like protein;(source:Araport11)
• TAIR Accession: locus:2121939
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT4G24710.1     AT4G24710.3     AT4G24710.2     AT4G24710.4

Plant Ontology Annotations:

• PO:0000037  — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
• PO:0009009  — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)

Gene Ontology:

• GO:0005634  — located in — nucleus
• GO:0051598  — involved in — meiotic recombination checkpoint signaling
• GO:0007129  — involved in — homologous chromosome pairing at meiosis
• GO:0051026  — acts upstream of or within — chiasma assembly
• GO:0000795  — part of — synaptonemal complex
• GO:0007130  — acts upstream of or within — synaptonemal complex assembly
• GO:0005634  — is active in — nucleus
• GO:0005737  — located in — cytoplasm
• GO:0005694  — located in — chromosome
• GO:0016887  — enables — ATP hydrolysis activity
• GO:0007131  — involved in — reciprocal meiotic recombination
• GO:0005694  — is active in — chromosome

Germplasm Phenotype:

• Atpch2-3  — Reduced fertility. Numerous gaps between seeds in siliques. Mean seed-set reduced.
• SAIL_1187_C06  — Reduced fertility. Numerous gaps between seeds in siliques. Mean seed-set reduced.
• SALK_031449C  — Reduced fertility. Numerous gaps between seeds in siliques. Mean seed-set reduced.

Function-related keywords:

• shoot axis apex ,  plant embryo ,  flower

Literature:

• Expression profiling of cytokinin action in Arabidopsis.   DOI:  10.1104/pp.103.021436 ;  PMID:  12913156
• Arabidopsis PCH2 Mediates Meiotic Chromosome Remodeling and Maturation of Crossovers.   DOI:  10.1371/journal.pgen.1005372 ;  PMID:  26182244
• Capturing the phosphorylation and protein interaction landscape of the plant TOR kinase.   DOI:  10.1038/s41477-019-0378-z ;  PMID:  30833711
• The Arabidopsis Cdk1/Cdk2 homolog CDKA;1 controls chromosome axis assembly during plant meiosis.   DOI:  10.15252/embj.2019101625 ;  PMID:  31556459
• State changes of the HORMA protein ASY1 are mediated by an interplay between its closure motif and PCH2.   DOI:  10.1093/nar/gkaa527 ;  PMID:  32558910
• COMET Functions as a PCH2 Cofactor in Regulating the HORMA Domain Protein ASY1.   DOI:  10.1016/j.cub.2020.07.089 ;  PMID:  32857973
• ZYP1-mediated recruitment of PCH2 to the synaptonemal complex remodels the chromosome axis leading to crossover restriction.   DOI:  10.1093/nar/gkac1160 ;  PMID:  36504011
• Coarsening dynamics can explain meiotic crossover patterning in both the presence and absence of the synaptonemal complex.   DOI:  10.7554/eLife.79408 ;  PMID:  36847348

Sequence: