Gene Details:

• Gene ID: AT4G31820
• Gene Symbol: ENP, MAB4, NPY1
• Gene Name: ENHANCER OF PINOID, MACCHI-BOU 4, NAKED PINS IN YUC MUTANTS 1
• Description: Phototropic-responsive NPH3 family protein;(source:Araport11)
• TAIR Accession:
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT4G31820.1     AT4G31820.2

Plant Ontology Annotations:

• PO:0000037  — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
• PO:0008019  — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
• PO:0009006  — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
• PO:0009009  — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
• PO:0009025  — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
• PO:0009031  — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
• PO:0009052  — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
• PO:0020030  — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
• PO:0020038  — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
• PO:0020100  — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
• PO:0020137  — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
• PO:0025022  — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)

Germplasm Phenotype:

• mab4-1  — Seedling defects include aberrant cotyledon number and cotyledon fusion. Floral defects include organ fusion, short valves and decreased valve number.
• npy1-1  — The npy1-1 mutation was uncovered in a genetic enhancer screen in the yuc1 yuc4-1 background. A small fraction (~2.5%) of npy1-1 single mutants have abnormal cotyledons, but they do not form the pin-like inflorescences observed in the npy1-1 yuc1 yuc4-1 triple mutants.
• npy1-1; yuc1; yuc4-1  — The triple mutant fails to produce cotyledons. True leaves develop, but show aberrant phyllotaxy. The mutant also fails to produce flowers on its pin-formed primary and lateral inflorescences. These phenotypes cannot be attributed to changes in the patterns of PIN1, PID, or MP transcription in the inflorescence.
• npy1-1; pid-101  — This double mutant fails to form cotyledons, first evident at the early heart stage of embryogenesis. It also has slightly shorter hypocotyls than wild type seedlings when grown in the dark and displays altered phyllotaxy. However, the light-grown hypocotyls and the roots of npy1-1 pid-101 mutant plants appear normal. In addition, the mutants can form true leaves and generate appropriate apical hooks in the dark.
• pid-3/mab4-1  — Severe defects in organogenesis. Mutants lack cotyledons and floral organs.

Function-related keywords:

• shoot axis apex ,  leaf lamina base ,  shoot system ,  plant embryo ,  vascular leaf ,  sepal ,  flower ,  inflorescence flower pedicel ,  cotyledon ,  petiole ,  hypocotyl ,  leaf apex ,  collective leaf structure

Literature:

• Cell cycle-regulated gene expression in Arabidopsis.   DOI:  10.1074/jbc.M207570200 ;  PMID:  12169696
• The gene ENHANCER OF PINOID controls cotyledon development in the Arabidopsis embryo.   DOI:  10.1242/dev.01969 ;  PMID:  16107478
• NPY1, a BTB-NPH3-like protein, plays a critical role in auxin-regulated organogenesis in Arabidopsis.   DOI:  10.1073/pnas.0708506104 ;  PMID:  18000043
• The gene MACCHI-BOU 4/ENHANCER OF PINOID encodes a NPH3-like protein and reveals similarities between organogenesis and phototropism at the molecular level.   DOI:  10.1242/dev.009654 ;  PMID:  17913786
• Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.   DOI:  10.1104/pp.108.121038 ;  PMID:  18650403
• NPY genes and AGC kinases define two key steps in auxin-mediated organogenesis in Arabidopsis.   DOI:  10.1073/pnas.0809761106 ;  PMID:  19075219
• NPY genes play an essential role in root gravitropic responses in Arabidopsis.   DOI:  10.1093/mp/ssq052 ;  PMID:  20833732
• Polar-localized NPH3-like proteins regulate polarity and endocytosis of PIN-FORMED auxin efflux carriers.   DOI:  10.1242/dev.057745 ;  PMID:  21490067
• Conversion of tryptophan to indole-3-acetic acid by TRYPTOPHAN AMINOTRANSFERASES OF ARABIDOPSIS and YUCCAs in Arabidopsis.   DOI:  10.1073/pnas.1108436108 ;  PMID:  22025721
• MAB4-induced auxin sink generates local auxin gradients in Arabidopsis organ formation.   DOI:  10.1073/pnas.1316109111 ;  PMID:  24395791
• SCI1 is a component of the auxin-dependent control of cell proliferation in Arabidopsis upper pistil.   DOI:  10.1016/j.plantsci.2014.09.003 ;  PMID:  25443839
• NCP1/AtMOB1A Plays Key Roles in Auxin-Mediated Arabidopsis Development.   DOI:  10.1371/journal.pgen.1005923 ;  PMID:  26942722
• A transcriptomics approach uncovers novel roles for poly(ADP-ribosyl)ation in the basal defense response in Arabidopsis thaliana.   DOI:  10.1371/journal.pone.0190268 ;  PMID:  29284022
• AGC kinases and MAB4/MEL proteins maintain PIN polarity by limiting lateral diffusion in plant cells.   DOI:  10.1016/j.cub.2021.02.028 ;  PMID:  33705718
• A high content in lipid-modified peripheral proteins and integral receptor kinases features in the arabidopsis plasma membrane proteome.   DOI:  10.1074/mcp.M700099-MCP200 ;  PMID:  17644812

Sequence: