Gene Details:

• Gene ID: AT5G08640
• Gene Symbol: ATFLS1, FLS, FLS1
• Gene Name: FLAVONOL SYNTHASE, flavonol synthase 1
• Description: flavonol synthase 1;(source:Araport11)
• TAIR Accession: locus:2159542
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT5G08640.1     AT5G08640.2

Plant Ontology Annotations:

• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)

Gene Ontology:

• GO:0005515  — enables — protein binding
• GO:0009733  — acts upstream of or within — response to auxin
• GO:0045431  — enables — flavonol synthase activity
• GO:0009813  — involved in — flavonoid biosynthetic process
• GO:0005737  — located in — cytoplasm
• GO:0009813  — acts upstream of or within — flavonoid biosynthetic process
• GO:0045486  — enables — naringenin 3-dioxygenase activity

Function-related keywords:

• root

Literature:

• Characterization of flavonol synthase and leucoanthocyanidin dioxygenase genes in Arabidopsis. Further evidence for differential regulation of "early" and "late" genes.   DOI:  10.1104/pp.113.4.1437 ;  PMID:  9112784
• Flavonol synthase gene expression during citrus fruit development.   DOI:  10.1034/j.1399-3054.2002.1140211.x ;  PMID:  11903972
• MAX1, a regulator of the flavonoid pathway, controls vegetative axillary bud outgrowth in Arabidopsis.   DOI:  10.1073/pnas.0509463102 ;  PMID:  16387852
• Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.   DOI:  10.1104/pp.108.121038 ;  PMID:  18650403
• The endogenous GL3, but not EGL3, gene is necessary for anthocyanin accumulation as induced by nitrogen depletion in Arabidopsis rosette stage leaves.   DOI:  10.1007/s00425-009-0978-3 ;  PMID:  19621239
• Karrikins enhance light responses during germination and seedling development in Arabidopsis thaliana.   DOI:  10.1073/pnas.0911635107 ;  PMID:  20351290
• Functional compensation of primary and secondary metabolites by duplicate genes in Arabidopsis thaliana.   DOI:  10.1093/molbev/msq204 ;  PMID:  20736450
• Auxin and ethylene induce flavonol accumulation through distinct transcriptional networks.   DOI:  10.1104/pp.111.172502 ;  PMID:  21427279
• Flavonols accumulate asymmetrically and affect auxin transport in Arabidopsis.   DOI:  10.1104/pp.111.175976 ;  PMID:  21502189
• Using biologically interrelated experiments to identify pathway genes in Arabidopsis.   DOI:  10.1093/bioinformatics/bts038 ;  PMID:  22271267
• Transcript profiling of cytokinin action in Arabidopsis roots and shoots discovers largely similar but also organ-specific responses.   DOI:  10.1186/1471-2229-12-112 ;  PMID:  22824128
• De novo production of the flavonoid naringenin in engineered Saccharomyces cerevisiae.   DOI:  10.1186/1475-2859-11-155 ;  PMID:  23216753
• A R2R3-MYB transcription factor, GmMYB12B2, affects the expression levels of flavonoid biosynthesis genes encoding key enzymes in transgenic Arabidopsis plants.   DOI:  10.1016/j.gene.2013.09.015 ;  PMID:  24060295
• AtROS1 overexpression provides evidence for epigenetic regulation of genes encoding enzymes of flavonoid biosynthesis and antioxidant pathways during salt stress in transgenic tobacco.   DOI:  10.1093/jxb/erv304 ;  PMID:  26116024
• Drastic anthocyanin increase in response to PAP1 overexpression in fls1 knockout mutant confers enhanced osmotic stress tolerance in Arabidopsis thaliana.   DOI:  10.1007/s00299-016-2040-9 ;  PMID:  27562381
• The Peroxidative Cleavage of Kaempferol Contributes to the Biosynthesis of the Benzenoid Moiety of Ubiquinone in Plants.   DOI:  10.1105/tpc.18.00688 ;  PMID:  30429224
• Involvement of the R2R3-MYB transcription factor MYB21 and its homologs in regulating flavonol accumulation in Arabidopsis stamen.   DOI:  10.1093/jxb/erab156 ;  PMID:  33831169
• BBX24 Interacts with DELLA to Regulate UV-B-Induced Photomorphogenesis in Arabidopsis thaliana.   DOI:  10.3390/ijms23137386 ;  PMID:  35806395
• ARF2 positively regulates flavonols and proanthocyanidins biosynthesis in Arabidopsis thaliana.   DOI:  10.1007/s00425-022-03936-w ;  PMID:  35857143
• Cell type-specific proteomics uncovers a RAF15-SnRK2.6/OST1 kinase cascade in guard cells.   DOI:  10.1111/jipb.13536 ;  PMID:  37226855
• Characterization of flavonol synthase and leucoanthocyanidin dioxygenase genes in Arabidopsis. Further evidence for differential regulation of "early" and "late" genes.   DOI:  10.1104/pp.113.4.1437 ;  PMID:  9112784

Sequence: