Gene Details:

• Gene ID: AT5G09790
• Gene Symbol: ATXR5, PDE336, SDG15
• Gene Name: ARABIDOPSIS TRITHORAX-RELATED PROTEIN 5, PIGMENT DEFECTIVE 336, SETDOMAIN GROUP 15
• Description: TRITHORAX-RELATED PROTEIN 5;(source:Araport11)
• TAIR Accession: locus:2144841
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT5G09790.1     AT5G09790.2

Gene Ontology:

• GO:0006275  — acts upstream of or within — regulation of DNA replication
• GO:0005634  — located in — nucleus
• GO:0005515  — enables — protein binding
• GO:0045892  — involved in — negative regulation of DNA-templated transcription
• GO:0009555  — acts upstream of or within — pollen development
• GO:0046976  — enables — histone H3K27 methyltransferase activity
• GO:0045944  — involved in — positive regulation of transcription by RNA polymerase II
• GO:0051726  — acts upstream of or within — regulation of cell cycle
• GO:0009294  — acts upstream of or within — DNA-mediated transformation
• GO:0003712  — enables — transcription coregulator activity
• GO:0009507  — located in — chloroplast

Germplasm Phenotype:

• atxr5 atrx6  — reduced H3K27me1 in vivo; partial heterochromatin decondensation; transcriptional activation of repressed heterochromatic elements

Literature:

• Comparative analysis of SET domain proteins in maize and Arabidopsis reveals multiple duplications preceding the divergence of monocots and dicots.   DOI:  10.1104/pp.102.013722 ;  PMID:  12805620
• Inactivation of the chloroplast ATP synthase gamma subunit results in high non-photochemical fluorescence quenching and altered nuclear gene expression in Arabidopsis thaliana.   DOI:  10.1074/jbc.M308435200 ;  PMID:  14576160
• A transcriptome-based characterization of habituation in plant tissue culture.   DOI:  10.1104/pp.105.076059 ;  PMID:  16489130
• Two cell-cycle regulated SET-domain proteins interact with proliferating cell nuclear antigen (PCNA) in Arabidopsis.   DOI:  10.1111/j.1365-313X.2006.02799.x ;  PMID:  16771839
• RNAi-mediated gene silencing reveals involvement of Arabidopsis chromatin-related genes in Agrobacterium-mediated root transformation.   DOI:  10.1073/pnas.0706986104 ;  PMID:  17827277
• Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis.   DOI:  10.1104/pp.108.126375 ;  PMID:  18775970
• Identification of nuclear genes encoding chloroplast-localized proteins required for embryo development in Arabidopsis.   DOI:  10.1104/pp.110.168120 ;  PMID:  21139083
• Comprehensive analysis of silencing mutants reveals complex regulation of the Arabidopsis methylome.   DOI:  10.1016/j.cell.2012.10.054 ;  PMID:  23313553
• Selective methylation of histone H3 variant H3.1 regulates heterochromatin replication.   DOI:  10.1126/science.1248357 ;  PMID:  24626927
• Identification of Multiple Proteins Coupling Transcriptional Gene Silencing to Genome Stability in Arabidopsis thaliana.   DOI:  10.1371/journal.pgen.1006092 ;  PMID:  27253878
• Molecular basis for the methylation specificity of ATXR5 for histone H3.   DOI:  10.1093/nar/gkx224 ;  PMID:  28383693
• Mutation of Arabidopsis SMC4 identifies condensin as a corepressor of pericentromeric transposons and conditionally expressed genes.   DOI:  10.1101/gad.301499.117 ;  PMID:  28882854
• Computational characterization of substrate and product specificities, and functionality of S-adenosylmethionine binding pocket in histone lysine methyltransferases from Arabidopsis, rice and maize.   DOI:  10.1002/prot.25399 ;  PMID:  29024026
• Arabidopsis Serrate Coordinates Histone Methyltransferases ATXR5/6 and RNA Processing Factor RDR6 to Regulate Transposon Expression.   DOI:  10.1016/j.devcel.2018.05.023 ;  PMID:  29920280
• H3.1K27me1 maintains transcriptional silencing and genome stability by preventing GCN5-mediated histone acetylation.   DOI:  10.1093/plcell/koaa027 ;  PMID:  33793815

Sequence: