Gene Details:

• Gene ID: AT5G13630
• Gene Symbol: ABAR, CCH, CCH1, CHLH, GUN5
• Gene Name: ABA-BINDING PROTEIN, CONDITIONAL CHLORINA, H SUBUNIT OF MG-CHELATASE, GENOMES UNCOUPLED 5
• Description: magnesium-chelatase subunit chlH, chloroplast, putative / Mg-protoporphyrin IX chelatase, putative (CHLH);(source:Araport11)
• TAIR Accession: locus:2173234
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT5G13630.1     AT5G13630.2

Plant Ontology Annotations:

• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0009025  — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)

Gene Ontology:

• GO:0044283  — acts upstream of or within — small molecule biosynthetic process
• GO:0019538  — acts upstream of or within — protein metabolic process
• GO:0071482  — acts upstream of or within — cellular response to light stimulus
• GO:0044255  — acts upstream of or within — cellular lipid metabolic process
• GO:0019438  — acts upstream of or within — aromatic compound biosynthetic process
• GO:0009409  — acts upstream of or within — response to cold
• GO:0003729  — enables — mRNA binding
• GO:1901362  — acts upstream of or within — organic cyclic compound biosynthetic process
• GO:0008610  — acts upstream of or within — lipid biosynthetic process
• GO:0005739  — located in — mitochondrion
• GO:0042548  — acts upstream of or within — regulation of photosynthesis, light reaction
• GO:0018130  — acts upstream of or within — heterocycle biosynthetic process
• GO:0009706  — located in — chloroplast inner membrane
• GO:0015995  — acts upstream of or within — chlorophyll biosynthetic process
• GO:0009507  — located in — chloroplast
• GO:0016070  — acts upstream of or within — RNA metabolic process
• GO:0044271  — acts upstream of or within — cellular nitrogen compound biosynthetic process
• GO:0009507  — is active in — chloroplast
• GO:0071483  — acts upstream of or within — cellular response to blue light
• GO:0015995  — involved in — chlorophyll biosynthetic process
• GO:0007623  — acts upstream of or within — circadian rhythm
• GO:0010007  — part of — magnesium chelatase complex

Germplasm Phenotype:

• CS6499  — Light-sensitive reduction of chlorophyll accumulation.
• CS6499  — cch mutant shows strong ABA insensitivity than wild-type in stomatal movement, including promotion of stomatal closure and inhibition of stomatal opening. The mutant also shows weak ABA insensitivity in germination and growth after germination.
• CS6499  — cch1-1 is paler than gun5-1.
• cch1 mutant  — leaky. Isolated as slow in greening after etiolated seedlings were placed in continuous light.
• lhcb6 cch  — lhcb6 cch double mutant shows ABA insensitivity than wild-type in stomatal movement, including promotion of stomatal closure and inhibition of stomatal opening, and the strength of the ABA insensitive phenotypes is comparable to that of the cch mutant, stronger than that of the lhcb6 single mutant and lhcb1 lhcb6 double mutant.

Function-related keywords:

• root ,  vascular leaf

Literature:

• Interactions between hy1 and gun mutants of Arabidopsis, and their implications for plastid/nuclear signalling.   DOI:  10.1046/j.1365-313x.2000.00936.x ;  PMID:  11135121
• Arabidopsis genomes uncoupled 5 (GUN5) mutant reveals the involvement of Mg-chelatase H subunit in plastid-to-nucleus signal transduction.   DOI:  10.1073/pnas.98.4.2053 ;  PMID:  11172074
• Global changes in gene expression in response to high light in Arabidopsis.   DOI:  10.1104/pp.005595 ;  PMID:  12427978
• Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.   DOI:  10.1105/tpc.016055 ;  PMID:  14671022
• An Arabidopsis mutant that is resistant to the protoporphyrinogen oxidase inhibitor acifluorfen shows regulatory changes in tetrapyrrole biosynthesis.   DOI:  10.1007/s00438-005-1129-6 ;  PMID:  15815918
• The analysis of the ChlI 1 and ChlI 2 genes using acifluorfen-resistant mutant of Arabidopsis thaliana.   DOI:  10.1007/s00425-006-0390-1 ;  PMID:  17123104
• Mutations in CHLOROPLAST RNA BINDING provide evidence for the involvement of the chloroplast in the regulation of the circadian clock in Arabidopsis.   DOI:  10.1111/j.1365-313X.2007.03160.x ;  PMID:  17617174
• Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.   DOI:  10.1104/pp.108.121038 ;  PMID:  18650403
• Light signalling pathways regulating the Mg-chelatase branchpoint of chlorophyll synthesis during de-etiolation in Arabidopsis thaliana.   DOI:  10.1039/b802596g ;  PMID:  18846290
• Functional analysis of Arabidopsis thaliana isoforms of the Mg-chelatase CHLI subunit.   DOI:  10.1039/b802604c ;  PMID:  18846282
• Phytochromes promote seedling light responses by inhibiting four negatively-acting phytochrome-interacting factors.   DOI:  10.1073/pnas.0812219106 ;  PMID:  19380720
• Gene expression profiling analysis of copper homeostasis in Arabidopsis thaliana.   DOI:  10.1016/j.bbrc.2010.01.111 ;  PMID:  20117084
• The Mg-chelatase H subunit of Arabidopsis antagonizes a group of WRKY transcription repressors to relieve ABA-responsive genes of inhibition.   DOI:  10.1105/tpc.110.073874 ;  PMID:  20543028
• ABA receptors: the START of a new paradigm in phytohormone signalling.   DOI:  10.1093/jxb/erq151 ;  PMID:  20522527
• Identification of nuclear genes encoding chloroplast-localized proteins required for embryo development in Arabidopsis.   DOI:  10.1104/pp.110.168120 ;  PMID:  21139083
• Arabidopsis 3-ketoacyl-CoA thiolase-2 (KAT2), an enzyme of fatty acid β-oxidation, is involved in ABA signal transduction.   DOI:  10.1093/pcp/pcr008 ;  PMID:  21257607
• Plastid signals confer Arabidopsis tolerance to water stress.   DOI:  NA ;  PMID:  21476436
• Deficiency in riboflavin biosynthesis affects tetrapyrrole biosynthesis in etiolated Arabidopsis tissue.   DOI:  10.1007/s11103-011-9846-1 ;  PMID:  22081402
• Light-harvesting chlorophyll a/b-binding proteins are required for stomatal response to abscisic acid in Arabidopsis.   DOI:  10.1093/jxb/err315 ;  PMID:  22143917
• Roles of the different components of magnesium chelatase in abscisic acid signal transduction.   DOI:  10.1007/s11103-012-9965-3 ;  PMID:  23011401
• Cochaperonin CPN20 negatively regulates abscisic acid signaling in Arabidopsis.   DOI:  10.1007/s11103-013-0082-8 ;  PMID:  23783410
• Identification of microRNA 395a in 24-epibrassinolide-regulated root growth of Arabidopsis thaliana using microRNA arrays.   DOI:  10.3390/ijms140714270 ;  PMID:  23839095
• Arabidopsis co-chaperonin CPN20 antagonizes Mg-chelatase H subunit to derepress ABA-responsive WRKY40 transcription repressor.   DOI:  10.1007/s11427-013-4587-9 ;  PMID:  24369350
• Arabidopsis pentatricopeptide repeat protein SOAR1 plays a critical role in abscisic acid signalling.   DOI:  10.1093/jxb/eru293 ;  PMID:  25005137
• A link between magnesium-chelatase H subunit and sucrose nonfermenting 1 (SNF1)-related protein kinase SnRK2.6/OST1 in Arabidopsis guard cell signalling in response to abscisic acid.   DOI:  10.1093/jxb/erv341 ;  PMID:  26175350
• The Recovery of Plastid Function Is Required for Optimal Response to Low Temperatures in Arabidopsis.   DOI:  10.1371/journal.pone.0138010 ;  PMID:  26366569
• An established Arabidopsis thaliana var. Landsberg erecta cell suspension culture accumulates chlorophyll and exhibits a stay-green phenotype in response to high external sucrose concentrations.   DOI:  10.1016/j.jplph.2016.05.008 ;  PMID:  27302005
• Identification of core subunits of photosystem II as action sites of HSP21, which is activated by the GUN5-mediated retrograde pathway in Arabidopsis.   DOI:  10.1111/tpj.13447 ;  PMID:  27943531
• Transcriptional Regulation of Tetrapyrrole Biosynthesis in Arabidopsis thaliana.   DOI:  10.3389/fpls.2016.01811 ;  PMID:  27990150
• A role of GUNs-Involved retrograde signaling in regulating Acetyl-CoA carboxylase 2 in Arabidopsis.   DOI:  10.1016/j.bbrc.2018.09.144 ;  PMID:  30292412
• Loss of fumarylacetoacetate hydrolase causes light-dependent increases in protochlorophyllide and cell death in Arabidopsis.   DOI:  10.1111/tpj.14235 ;  PMID:  30666736
• Extensive Posttranscriptional Regulation of Nuclear Gene Expression by Plastid Retrograde Signals.   DOI:  10.1104/pp.19.00421 ;  PMID:  31138622
• Discovering the RNA-Binding Proteome of Plant Leaves with an Improved RNA Interactome Capture Method.   DOI:  10.3390/biom10040661 ;  PMID:  32344669
• Identification of small non-coding RNAs responsive to GUN1 and GUN5 related retrograde signals in Arabidopsis thaliana.   DOI:  10.1111/tpj.14912 ;  PMID:  32639635
• Tetrapyrrole biosynthesis pathway regulates plastid-to-nucleus signaling by controlling plastid gene expression in plants.   DOI:  10.1016/j.xplc.2022.100411 ;  PMID:  35836377
• Arabidopsis EXECUTER1 interacts with WRKY transcription factors to mediate plastid-to-nucleus singlet oxygen signaling.   DOI:  10.1093/plcell/koac330 ;  PMID:  36423342
• Shade represses photosynthetic genes by disrupting the DNA binding of GOLDEN2-LIKE1.   DOI:  10.1093/plphys/kiad029 ;  PMID:  36702576
• Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.   DOI:  10.1105/tpc.016055 ;  PMID:  14671022
• The Arabidopsis thaliana chloroplast proteome reveals pathway abundance and novel protein functions.   DOI:  10.1016/j.cub.2004.02.039 ;  PMID:  15028209
• Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.   DOI:  10.1371/journal.pone.0001994 ;  PMID:  18431481
• Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.   DOI:  10.1371/journal.pone.0001994 ;  PMID:  18431481

Sequence: