Gene Details:

• Gene ID: AT5G14250
• Gene Symbol: COP13, CSN3, FUS11
• Gene Name: CONSTITUTIVE PHOTOMORPHOGENIC 13, COP9 SIGNALOSOME SUBUNIT 3, FUSCA 11
• Description: Proteasome component (PCI) domain protein;(source:Araport11)
• TAIR Accession: locus:2145638
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT5G14250.1     AT5G14250.2

Plant Ontology Annotations:

• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)

Gene Ontology:

• GO:0006511  — involved in — ubiquitin-dependent protein catabolic process
• GO:0005515  — enables — protein binding
• GO:0010971  — acts upstream of or within — positive regulation of G2/M transition of mitotic cell cycle
• GO:0000338  — acts upstream of or within — protein deneddylation
• GO:0008180  — part of — COP9 signalosome
• GO:0009640  — acts upstream of or within — photomorphogenesis
• GO:0008180  — located in — COP9 signalosome

Germplasm Phenotype:

• CS5224  — In the homozygous progeny, anthocyanin accumulation (purple coloration) in the cotelydons of developing embryos.
• CS5224  — In the homozygous progeny, dark purple seeds.
• CS5224  — Mutation is lethal in the homozygous state.
• SALK_000593  — constitutive photomorphogenesis
• fus11-U203  — In the homozygous mutant progeny, CSN3, CSN1 and CSN5 were all absent from the COP9 signalosome , although CSN5 could be found exclusively in the monomeric form.
• fus11-U203  — In the homozygous progeny, anthocyanin accumulation (purple coloration) in the cotelydons of developing embryos.
• fus11-U203  — Mutation is lethal in the homozygous state.

Function-related keywords:

• root

Literature:

• The COP9 complex is conserved between plants and mammals and is related to the 26S proteasome regulatory complex.   DOI:  10.1016/s0960-9822(07)00372-7 ;  PMID:  9707402
• The COP9 signalosome: from light signaling to general developmental regulation and back.   DOI:  10.1016/s1369-5266(00)00101-1 ;  PMID:  11019806
• A role of Arabidopsis COP9 signalosome in multifaceted developmental processes revealed by the characterization of its subunit 3.   DOI:  10.1242/dev.128.21.4277 ;  PMID:  11684663
• Subunit interaction maps for the regulatory particle of the 26S proteasome and the COP9 signalosome.   DOI:  10.1093/emboj/20.24.7096 ;  PMID:  11742986
• Arabidopsis CULLIN4 Forms an E3 Ubiquitin Ligase with RBX1 and the CDD Complex in Mediating Light Control of Development.   DOI:  10.1105/tpc.106.043224 ;  PMID:  16844902
• Role of the MPN subunits in COP9 signalosome assembly and activity, and their regulatory interaction with Arabidopsis Cullin3-based E3 ligases.   DOI:  10.1105/tpc.106.047571 ;  PMID:  17307927
• The Arabidopsis COP9 signalosome is essential for G2 phase progression and genomic stability.   DOI:  10.1242/dev.020743 ;  PMID:  18434413
• Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.   DOI:  10.1104/pp.108.121038 ;  PMID:  18650403
• SMALL ACIDIC PROTEIN1 acts with RUB modification components, the COP9 signalosome, and AXR1 to regulate growth and development of Arabidopsis.   DOI:  10.1104/pp.111.188409 ;  PMID:  22576848
• Systematic identification of functional plant modules through the integration of complementary data sources.   DOI:  10.1104/pp.112.196725 ;  PMID:  22589469
• The eta7/csn3-3 auxin response mutant of Arabidopsis defines a novel function for the CSN3 subunit of the COP9 signalosome.   DOI:  10.1371/journal.pone.0066578 ;  PMID:  23762492
• The COP9 signalosome: from light signaling to general developmental regulation and back.   DOI:  10.1016/s1369-5266(00)00101-1 ;  PMID:  11019806

Sequence: