Gene Details:
- Gene ID: AT5G17220
- Gene Symbol: ATGSTF12, GST26, GSTF12, TT19
- Gene Name: ARABIDOPSIS THALIANA GLUTATHIONE S-TRANSFERASE PHI 12, GLUTATHIONE S-TRANSFERASE 26, glutathione S-transferase phi 12, TRANSPARENT TESTA 19
- Description: glutathione S-transferase phi 12;(source:Araport11)
- TAIR Accession: locus:2167215
- Genome: Araport11_genome_release
- Species: Arabidopsis thaliana
Transcripts:
Gene Ontology:
- GO:0009407 — acts upstream of or within — toxin catabolic process
- GO:0043169 — enables — cation binding
- GO:0005737 — is active in — cytoplasm
- GO:0004364 — enables — glutathione transferase activity
- GO:0043295 — enables — glutathione binding
- GO:0005634 — located in — nucleus
- GO:0009705 — located in — plant-type vacuole membrane
- GO:0006749 — involved in — glutathione metabolic process
- GO:1900384 — acts upstream of or within — regulation of flavonol biosynthetic process
Germplasm Phenotype:
- CS2105587 — pale brown seeds, lacks anthocyanins
- tt19 — brown seed coat, however reduced level of flavonoids in the tapetum cells. Unlike the wild type where flavonoids are accumulated in the tapetosomes in the tapetum cells, the mutant has flavonoids accumulated in the cytosol
Literature:
- Probing the diversity of the Arabidopsis glutathione S-transferase gene family. DOI: 10.1023/a:1015557300450 ; PMID: 12090627
- Large-scale identification of leaf senescence-associated genes. DOI: 10.1046/j.1365-313x.2003.01908.x ; PMID: 14617064
- When defense pathways collide. The response of Arabidopsis to a combination of drought and heat stress. DOI: 10.1104/pp.103.033431 ; PMID: 15047901
- Responses of primary and secondary metabolism to sugar accumulation revealed by microarray expression analysis of the Arabidopsis mutant, pho3. DOI: 10.1093/jxb/erh143 ; PMID: 15133053
- Molecular phenotyping of the pal1 and pal2 mutants of Arabidopsis thaliana reveals far-reaching consequences on phenylpropanoid, amino acid, and carbohydrate metabolism. DOI: 10.1105/tpc.104.023705 ; PMID: 15377757
- Functional genomics by integrated analysis of metabolome and transcriptome of Arabidopsis plants over-expressing an MYB transcription factor. DOI: 10.1111/j.1365-313X.2005.02371.x ; PMID: 15807784
- Analysis of the female gametophyte transcriptome of Arabidopsis by comparative expression profiling. DOI: 10.1104/pp.105.067314 ; PMID: 16299181
- A coumaroyl-ester-3-hydroxylase insertion mutant reveals the existence of nonredundant meta-hydroxylation pathways and essential roles for phenolic precursors in cell expansion and plant growth. DOI: 10.1104/pp.105.069690 ; PMID: 16377748
- A UV-B-specific signaling component orchestrates plant UV protection. DOI: 10.1073/pnas.0507187102 ; PMID: 16330762
- MAX1, a regulator of the flavonoid pathway, controls vegetative axillary bud outgrowth in Arabidopsis. DOI: 10.1073/pnas.0509463102 ; PMID: 16387852
- Anthocyaninless1 gene of Arabidopsis thaliana encodes a UDP-glucose:flavonoid-3-O-glucosyltransferase. DOI: 10.1007/s10265-006-0067-7 ; PMID: 17277900
- Impact of AtNHX1, a vacuolar Na+/H+ antiporter, upon gene expression during and long-term salt stress in Arabidopsis thaliana. DOI: 10.1186/1471-2229-7-18 ; PMID: 17411438
- Transcription factor AtDOF4;2 affects phenylpropanoid metabolism in Arabidopsis thaliana. DOI: 10.1111/j.1469-8137.2007.02129.x ; PMID: 17635218
- MYC2 differentially modulates diverse jasmonate-dependent functions in Arabidopsis. DOI: 10.1105/tpc.106.048017 ; PMID: 17616737
- The Arabidopsis MATE transporter TT12 acts as a vacuolar flavonoid/H+ -antiporter active in proanthocyanidin-accumulating cells of the seed coat. DOI: 10.1105/tpc.106.046029 ; PMID: 17601828
- Simultaneous interaction of Arabidopsis thaliana with Bradyrhizobium Sp. strain ORS278 and Pseudomonas syringae pv. tomato DC3000 leads to complex transcriptome changes. DOI: 10.1094/MPMI-21-2-0244 ; PMID: 18184068
- The absence of ALTERNATIVE OXIDASE1a in Arabidopsis results in acute sensitivity to combined light and drought stress. DOI: 10.1104/pp.107.115121 ; PMID: 18424626
- Comprehensive flavonol profiling and transcriptome coexpression analysis leading to decoding gene-metabolite correlations in Arabidopsis. DOI: 10.1105/tpc.108.058040 ; PMID: 18757557
- Accumulation of flavonoids in an ntra ntrb mutant leads to tolerance to UV-C. DOI: 10.1093/mp/ssn065 ; PMID: 19825611
- Metabolic profiling and cytological analysis of proanthocyanidins in immature seeds of Arabidopsis thaliana flavonoid accumulation mutants. DOI: 10.1111/j.1365-313X.2010.04174.x ; PMID: 20180920
- Systems analysis of seed filling in Arabidopsis: using general linear modeling to assess concordance of transcript and protein expression. DOI: 10.1104/pp.109.152413 ; PMID: 20118269
- The Arabidopsis tt19-4 mutant differentially accumulates proanthocyanidin and anthocyanin through a 3' amino acid substitution in glutathione S-transferase. DOI: 10.1111/j.1365-3040.2010.02249.x ; PMID: 21054438
- Complexity and robustness of the flavonoid transcriptional regulatory network revealed by comprehensive analyses of MYB-bHLH-WDR complexes and their targets in Arabidopsis seed. DOI: 10.1111/nph.12620 ; PMID: 24299194
- Anthocyanin Vacuolar Inclusions Form by a Microautophagy Mechanism. DOI: 10.1105/tpc.15.00589 ; PMID: 26342015
- Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana. DOI: 10.1111/nph.14242 ; PMID: 27768815
- Functional characterization of a heterologously expressed Brassica napus WRKY41-1 transcription factor in regulating anthocyanin biosynthesis in Arabidopsis thaliana. DOI: 10.1016/j.plantsci.2017.12.010 ; PMID: 29362083
- Synergy between the anthocyanin and RDR6/SGS3/DCL4 siRNA pathways expose hidden features of Arabidopsis carbon metabolism. DOI: 10.1038/s41467-020-16289-3 ; PMID: 32415123
- ARF2 positively regulates flavonols and proanthocyanidins biosynthesis in Arabidopsis thaliana. DOI: 10.1007/s00425-022-03936-w ; PMID: 35857143
- MAX1, a regulator of the flavonoid pathway, controls vegetative axillary bud outgrowth in Arabidopsis. DOI: 10.1073/pnas.0509463102 ; PMID: 16387852
- Identification of genes expressed in vascular tissues using NPA-induced vascular overgrowth in Arabidopsis. DOI: 10.1093/pcp/pcn023 ; PMID: 18296723
Sequence:
cDNA Sequence
- >AT5G17220.1 ACATCTACTCTCATTTCTTCTCATTTATAAACCAGTTTGATAGACAAGATATTAATAAGTGCATATAGTAAAATCTTTCTTATTCGTAACAAAGTTATTGTAAACTTATAGAATGGTTGTGAAACTATATGGACAGGTAACAGCAGCTTGTCCACAAAGAGTCTTGCTTTGTTTTCTCGAGAAAGGAATTGAATTTGAGATTATTCATATCGATCTTGATACATTTGAGCAAAAAAAACCAGAACATCTTCTTCGTCAGCCATTTGGTCAAGTTCCAGCCATAGAAGATGGAGATTTCAAGCTTTTTGAATCACGAGCCATCGCGAGATACTACGCTACCAAGTTCGCGGACCAAGGCACGAACCTTTTGGGCAAGTCTCTAGAGCACCGAGCCATCGTGGACCAGTGGGCTGACGTGGAGACCTATTACTTCAACGTTCTGGCCCAACCCCTCGTGATTAACCTAATCATCAAGCCTAGGTTAGGCGAGAAATGTGACGTCGTTTTGGTCGAGGATCTCAAAGTGAAGCTAGGAGTGGTCTTGGACATATACAATAACCGGCTTTCTTCGAACCGGTTTTTGGCTGGTGAAGAATTCACTATGGCTGATTTGACGCACATGCCGGCGATGGGGTACTTGATGAGTATAACCGATATAAACCAGATGGTTAAGGCTCGGGGTAGTTTTAACCGGTGGTGGGAAGAGATTTCGGATAGACCGTCTTGGAAGAAGCTTATGGTGCTGGCTGGTCACTGAATTAGCTCCAATTTATGATGATCTGAAGAACCAAATAAGCTTTATAGTTTCTGTTTTATGTTTGTGTTGTTTTGTACGTTTCAGTAATAAATTCAATATACTTTTAAGATTCATGTCAATGCTAAGACCATAGTTCTCTATTCTTAAGTTTTTACTCTATTTTTGAGTGAGATATAAAATGGGGTTAAAATAGAAGTGGAGTTTTTACATAGTATACAAGGTTACTCACTTGTACTATTATTCGAATATAAGAAGAACTTCTTTCTGTATGTATATCACAAGATTATTTCATCAACCAAAAATTGTATATCCCCTCATTAGGCCAAGAGAACTATAACT
CDS Sequence
Protein Sequence