Gene Details:

• Gene ID: AT5G20990
• Gene Symbol: B73, CHL6, CNX, CNX1, SIR4
• Gene Name: CHLORATE RESISTANT 6, CO-FACTOR FOR NITRATE REDUCTASE AND XANTHINE DEHYDROGENASE, CO-FACTOR FOR NITRATE REDUCTASE AND XANTHINE DEHYDROGENASE 1, SIRTINOL 4
• Description: molybdopterin biosynthesis CNX1 protein / molybdenum cofactor biosynthesis enzyme CNX1 (CNX1);(source:Araport11)
• TAIR Accession: locus:2147157
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT5G20990.1     AT5G20990.2     AT5G20990.3

Plant Ontology Annotations:

• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)

Gene Ontology:

• GO:0006777  — involved in — Mo-molybdopterin cofactor biosynthetic process
• GO:0005737  — located in — cytoplasm
• GO:0005634  — located in — nucleus
• GO:0005737  — is active in — cytoplasm
• GO:0006777  — acts upstream of or within — Mo-molybdopterin cofactor biosynthetic process
• GO:0030151  — enables — molybdenum ion binding
• GO:0009734  — acts upstream of or within — auxin-activated signaling pathway
• GO:0005829  — is active in — cytosol
• GO:0061599  — enables — molybdopterin molybdotransferase activity
• GO:0061598  — enables — molybdopterin adenylyltransferase activity

Germplasm Phenotype:

• CS203  — chlorate resistant due to reduced nitrate reductase activity, about 10 percent of the wild-type level; reduced levels of the nitrate reductase cofactor molybenum-pterin (Mo Co); poor growth on nitrate medium.

Function-related keywords:

• root

Literature:

• Genetic and chemical analyses of the action mechanisms of sirtinol in Arabidopsis.   DOI:  10.1073/pnas.0500185102 ;  PMID:  15710899
• Species specific amino acid sequence-protein local structure relationships: An analysis in the light of a structural alphabet.   DOI:  10.1016/j.jtbi.2011.01.047 ;  PMID:  21333657
• Identification of a protein-protein interaction network downstream of molybdenum cofactor biosynthesis in Arabidopsis thaliana.   DOI:  10.1016/j.jplph.2016.10.002 ;  PMID:  27792900
• Genetic dissection of cyclic pyranopterin monophosphate biosynthesis in plant mitochondria.   DOI:  10.1042/BCJ20170559 ;  PMID:  29247140
• Physiological Importance of Molybdate Transporter Family 1 in Feeding the Molybdenum Cofactor Biosynthesis Pathway in Arabidopsis thaliana.   DOI:  10.3390/molecules27103158 ;  PMID:  35630635
• Cadmium treatment induces endoplasmic reticulum stress and unfolded protein response in Arabidopsisthaliana.   DOI:  10.1016/j.plaphy.2023.01.056 ;  PMID:  36736010

Sequence: