Gene Details:

• Gene ID: AT5G35550
• Gene Symbol: ATMYB123, ATTT2, MYB123, TT2
• Gene Name: MYB DOMAIN PROTEIN 123, MYB DOMAIN PROTEIN 123, TRANSPARENT TESTA 2
• Description: Duplicated homeodomain-like superfamily protein;(source:Araport11)
• TAIR Accession: locus:2169538
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT5G35550.1     AT5G35550.2

Gene Ontology:

• GO:0003700  — enables — DNA-binding transcription factor activity
• GO:0005515  — enables — protein binding
• GO:0010023  — acts upstream of or within — proanthocyanidin biosynthetic process
• GO:0006633  — acts upstream of or within — fatty acid biosynthetic process
• GO:0000976  — enables — transcription cis-regulatory region binding
• GO:0030154  — involved in — cell differentiation
• GO:0005634  — is active in — nucleus
• GO:0005634  — located in — nucleus
• GO:0006355  — involved in — regulation of DNA-templated transcription
• GO:0006970  — acts upstream of or within — response to osmotic stress

Literature:

• The TT8 gene encodes a basic helix-loop-helix domain protein required for expression of DFR and BAN genes in Arabidopsis siliques.   DOI:  10.1105/tpc.12.10.1863 ;  PMID:  11041882
• Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.   DOI:  10.1126/science.290.5499.2105 ;  PMID:  11118137
• The R2R3-MYB gene family in Arabidopsis thaliana.   DOI:  10.1016/s1369-5266(00)00199-0 ;  PMID:  11597504
• The Arabidopsis TT2 gene encodes an R2R3 MYB domain protein that acts as a key determinant for proanthocyanidin accumulation in developing seed.   DOI:  10.1105/tpc.010098 ;  PMID:  11549766
• Metabolic engineering of proanthocyanidins by ectopic expression of transcription factors in Arabidopsis thaliana.   DOI:  10.1111/j.1365-313X.2005.02510.x ;  PMID:  16167896
• TT8 controls its own expression in a feedback regulation involving TTG1 and homologous MYB and bHLH factors, allowing a strong and cell-specific accumulation of flavonoids in Arabidopsis thaliana.   DOI:  10.1111/j.1365-313X.2006.02733.x ;  PMID:  16709193
• Arabidopsis TRANSPARENT TESTA GLABRA2 is directly regulated by R2R3 MYB transcription factors and is involved in regulation of GLABRA2 transcription in epidermal differentiation.   DOI:  10.1105/tpc.107.052274 ;  PMID:  17766401
• TTG1 complex MYBs, MYB5 and TT2, control outer seed coat differentiation.   DOI:  10.1016/j.ydbio.2008.10.005 ;  PMID:  18992236
• The promoter of the Arabidopsis thaliana BAN gene is active in proanthocyanidin-accumulating cells of the Brassica napus seed coat.   DOI:  10.1007/s00299-008-0667-x ;  PMID:  19153740
• Architectural phenotypes in the transparent testa mutants of Arabidopsis thaliana.   DOI:  10.1093/jxb/ern323 ;  PMID:  19129166
• A WD40-repeat gene from Malus x domestica is a functional homologue of Arabidopsis thaliana TRANSPARENT TESTA GLABRA1.   DOI:  10.1007/s00299-010-0821-0 ;  PMID:  20107808
• TRANSPARENT TESTA1 interacts with R2R3-MYB factors and affects early and late steps of flavonoid biosynthesis in the endothelium of Arabidopsis thaliana seeds.   DOI:  10.1111/j.1365-313X.2011.04603.x ;  PMID:  21477081
• A new system for fast and quantitative analysis of heterologous gene expression in plants.   DOI:  10.1111/j.1469-8137.2011.03936.x ;  PMID:  22023451
• Proanthocyanidins inhibit seed germination by maintaining a high level of abscisic acid in Arabidopsis thaliana.   DOI:  10.1111/j.1744-7909.2012.01142.x ;  PMID:  22765383
• Identification of key amino acids for the evolution of promoter target specificity of anthocyanin and proanthocyanidin regulating MYB factors.   DOI:  10.1007/s11103-013-0074-8 ;  PMID:  23689818
• The TRANSPLANTA collection of Arabidopsis lines: a resource for functional analysis of transcription factors based on their conditional overexpression.   DOI:  10.1111/tpj.12443 ;  PMID:  24456507
• TRANSPARENT TESTA2 regulates embryonic fatty acid biosynthesis by targeting FUSCA3 during the early developmental stage of Arabidopsis seeds.   DOI:  10.1111/tpj.12426 ;  PMID:  24397827
• Starting to gel: how Arabidopsis seed coat epidermal cells produce specialized secondary cell walls.   DOI:  10.3390/ijms16023452 ;  PMID:  25658798
• The rolB gene activates secondary metabolism in Arabidopsis calli via selective activation of genes encoding MYB and bHLH transcription factors.   DOI:  10.1016/j.plaphy.2016.02.015 ;  PMID:  26913794
• Two IIIf Clade-bHLHs from Freesia hybrida Play Divergent Roles in Flavonoid Biosynthesis and Trichome Formation when Ectopically Expressed in Arabidopsis.   DOI:  10.1038/srep30514 ;  PMID:  27465838
• Characterization of the cis elements in the proximal promoter regions of the anthocyanin pathway genes reveals a common regulatory logic that governs pathway regulation.   DOI:  10.1093/jxb/erv173 ;  PMID:  25911741
• Site-specific phosphorylation of TRANSPARENT TESTA GLABRA1 mediates carbon partitioning in Arabidopsis seeds.   DOI:  10.1038/s41467-018-03013-5 ;  PMID:  29422671
• Insights into the role of transcription factors controlling mucilage production in the Arabidopsis seed coat.   DOI:  10.1016/j.plantsci.2018.04.021 ;  PMID:  29807590
• MYB-bHLH-TTG1 Regulates Arabidopsis Seed Coat Biosynthesis Pathways Directly and Indirectly via Multiple Tiers of Transcription Factors.   DOI:  10.1093/pcp/pcaa027 ;  PMID:  32154880
• The Seed Development Factors TT2 and MYB5 Regulate Heat Stress Response in Arabidopsis.   DOI:  10.3390/genes12050746 ;  PMID:  34063415
• ARF2 positively regulates flavonols and proanthocyanidins biosynthesis in Arabidopsis thaliana.   DOI:  10.1007/s00425-022-03936-w ;  PMID:  35857143
• Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.   DOI:  10.1126/science.290.5499.2105 ;  PMID:  11118137

Sequence: