Gene Details:

  • Gene ID: CotAD_19088
  • Gene Symbol: GhMPK4
  • Gene Name: mitogen-activated protein kinase 4
  • Genome: TM1_NBI
  • Species: Gossypium hirsutum

Functional Descriptions:

  • Scaffold protein GhMORG1 enhances the resistance of cotton to Fusarium oxysporum by facilitating the GhMKK6-GhMPK4 cascade.
  • GhMORG1 interacted with GhMKK6 and GhMPK4, and the overexpression of GhMORG1 in cotton protoplasts dramatically increased the activity of the GhMKK6-GhMPK4 cascade.
  • Identified as putative substrates of the GhMORG1-dependent GhMKK6-GhMPK4 cascade and participated in the resistance of cotton to F. oxysporum.
  • These results indicated that GhMORG1 regulated the resistance of cotton to F. oxysporum by mediating the GhMKK6-GhMPK4 cascade.
  • These results suggest that GhMORG1 regulates several different disease resistance processes by facilitating the phosphorylation of GhMKK6-GhMPK4 cascade substrates. Taken together, these findings reveal a new plant MAPK scaffold protein and provide insights into the mechanism of plant resistance to pathogens.

Literature:

Gene Resources:

  • NCBI ID:
  • UniProt accessions:

Orthologs:

Sequences:

cDNA Sequence
CDS Sequence
Protein Sequence