Gene Details:
- Gene ID:
- Gene Symbol: GhJAZ24
- Gene Name:
- Genome: TM1_NBI
- Species: Gossypium hirsutum
Functional Descriptions:
- Here we showed that overexpression of jasmonate ZIM-domain (JAZ) protein GhJAZ24 confers resistance to cotton bollworm and FAW, while also causing sterility in transgenic cotton by recruiting TOPLESS and histone deacetylase 6.
- Identified the NGR motif of GhJAZ24 that recognizes and binds the aminopeptidase N receptor, enabling GhJAZ24 to enter cells and disrupt histone deacetylase 3, leading to cell death.
- To overcome plant sterility associated with GhJAZ24 overexpression, we developed iJAZ (i, induced), an approach involving damage-induced expression and a switch from intracellular to extracellular localization of GhJAZ24.
- iJAZ transgenic cotton maintained fertility and showed insecticidal activity against cotton bollworm and FAW.
Function-related keywords:
- resistance , fertility , sterility , jasmonate , cell-death , protein
Literature:
- iJAZ-based approach to engineer lepidopteran pest resistance in multiple crop species. DOI: 10.1038/s41477-024-01682-3 ; PMID: 38684916
Related News:
Gene Resources:
Orthologs:
Sequences:
cDNA Sequence
CDS Sequence
Protein Sequence