Gene Details:

• Gene ID:
• Gene Symbol: MdOSC1
• Gene Name: oxidosqualene cyclase1
• Genome: Golden ASM211411v1
• Species: Malus domestica

Functional Descriptions:

• The gene expression of MdOSC1 was linked to the concentrations of ursolic and oleanolic acid, whereas the expression of MdOSC5 was correlated with the concentrations of betulinic acid and its caffeate derivatives.
• The gene expression of four OSC genes (MdOSC1, MdOSC3, and MdOSC4 and MdOSC5) as well as the cytochrome P450 was also measured in a collection of 20 contrasting apple cultivars (in terms of triterpene accumulation) and revealed the key roles played by MdOSC1 and MdOSC5 in explaining the concentrations of α-amyrin and lupeol derivatives, respectively.
• Positive and significant correlations were found between the expression of MdOSC1 and the contents of UA and OA, as well as between MdOSC5 expression and BA and triterpene-caffeate concentrations.
• This study also suggests that MdOSC1 and MdOSC5 are key genes in apple fruit triterpene biosynthesis.

Function-related keywords:

Literature:

• Multifunctional oxidosqualene cyclases and cytochrome P450 involved in the biosynthesis of apple fruit triterpenic acids.   DOI:  10.1111/nph.13996 ;  PMID:  27214242

Related News:

Gene Resources:

• NCBI ID: FJ032006
• UniProt accessions:

Orthologs:

Sequences: