Gene Details:

• Gene ID:
• Gene Symbol: MdOSC5
• Gene Name: oxidosqualene cyclase5
• Genome: Golden ASM211411v1
• Species: Malus domestica

Functional Descriptions:

• We used a homology-based approach to identify and functionally characterize two new oxidosqualene cyclases (MdOSC4 and MdOSC5) and one cytochrome P450 (CYP716A175).
• MdOSC5 cyclizes 2,3-oxidosqualene into lupeol and β-amyrin at a ratio of 95 : 5.
• The gene expression of MdOSC1 was linked to the concentrations of ursolic and oleanolic acid, whereas the expression of MdOSC5 was correlated with the concentrations of betulinic acid and its caffeate derivatives.
• This study also suggests that MdOSC1 and MdOSC5 are key genes in apple fruit triterpene biosynthesis.

Function-related keywords:

Literature:

• Multifunctional oxidosqualene cyclases and cytochrome P450 involved in the biosynthesis of apple fruit triterpenic acids.   DOI:  10.1111/nph.13996 ;  PMID:  27214242

Related News:

Gene Resources:

• NCBI ID: KT383436
• UniProt accessions:

Orthologs:

Sequences: