Gene Details:

• MSU gene ID: LOC_Os02g17940
• RAPdb gene ID: Os02g0280700
• Gene Symbol: HIS1
• Genome: MSU7 ,  IRGSP-1.0
• Species: Oryza sativa

Functional Descriptions:

• Here we identify a rice gene, HIS1 (HPPD INHIBITOR SENSITIVE 1), that confers resistance to BBC and other 尾-triketone herbicides.
• Forced expression of HIS1 in Arabidopsis conferred resistance not only to BBC but also to four additional 尾-triketone herbicides.
• HIS1 may prove useful for breeding herbicide-resistant crops.
• Exploring Natural Allelic Variations of the β-Triketone Herbicide Resistance Gene HIS1 for Application in indica Rice and Particularly in Two-Line Hybrid Rice.
• Results: By analyzing haplotypes of the bTHs broad-spectrum resistance gene HIS1 and phenotypes for BBC in 493 major indica rice accessions in China, we identified a novel non-functional allelic variant of HIS1 in addition to the previously reported 28-bp deletion.
• Finally, allelic variations of the HIS1 gene may also play an important role in the mechanized seed production of hybrid rice.
• In addition, due to natural allelic variations of the HIS1 gene in the sterile and restorer lines, some two-line hybrid sterile lines were sensitive to bTHs, and the corresponding restorers were resistant.

Function-related keywords:

• resistance ,  breeding ,  seed ,  sterile ,  resistant ,  herbicide-resistance

Literature:

• A rice gene that confers broad-spectrum resistance to β-triketone herbicides .  DOI:  10.1126/science.aax0379 ;  PMID:  31346065
• Exploring Natural Allelic Variations of the β-Triketone Herbicide Resistance Gene HIS1 for Application in indica Rice and Particularly in Two-Line Hybrid Rice .  DOI:  10.1186/s12284-020-00448-7 ;  PMID:  33415497

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions:

Sequences: