Gene Details:
- MSU gene ID: LOC_Os05g02260
- RAPdb gene ID: Os05g0113500
- Gene Symbol: bip130
- Genome: MSU7 , IRGSP-1.0
- Species: Oryza sativa
Functional Descriptions:
- Phosphorylation of bip130 by OsMPK1 regulates abscisic acid-induced antioxidant defense in rice.
- A transient expression analysis in combination with mutant analysis in rice protoplasts revealed that bip130 is required for ABA-induced antioxidant defense in an OsMPK1-dependent manner.
- Furthermore, bip130 can be phosphorylated by OsMPK1 at Thr-153 in vitro, and Thr-153 is essential for the ABA-induced antioxidant defense by OsMPK1.
- These results reveal that OsMPK1 phosphorylates bip130 at Thr-153 to regulate ABA-induced antioxidant defense.
Function-related keywords:
Literature:
- Phosphorylation of bip130 by OsMPK1 regulates abscisic acid-induced antioxidant defense in rice . DOI: 10.1016/j.bbrc.2019.04.183 ; PMID: 31078272
Related News:
Gene Resources:
Sequences:
cDNA Sequence
- >LOC_Os05g02260.3 cDNA AACCGTCAAGAGAGAAGTATTCGGAAAGAAGAGAAGGAAAAAAAGAATTTTTAGAGAGAGGAGGAAAAAAAATATCCCCAATCCCATCATCCCTTCACCCACCCGCACGCGTCTCCTCCGACTCCGATCCGAGCTCCAGATCTGCGGCGCCGGCGACCAACCTCTCCGGCGGCGGGGGCGGCGGCGGAGATCCACGATGCCTTCGTCGGAGCAGGGGGCCTCGCCCCTGCGCCGCCTCCTCCGCGTCGACGCCCTCGTCCTCCCCTCCGCTTGCTCCCACCGCCTTAAGCCTTGGTCTCTCCATCCCCACCTCCTCTCATCCTCCTAACGCCATCCAATCTCTCTTCTCCCCGTCTCTTTCTCCTGCTCCCCGTTGCCCTCCCATTTCTTCCCCTTTTCTTCTCGTAGCTATAGGGTGATACACTTCTCTGATTATTGTTGTTGTTCTTCCCGTGCTGATTTGGATTTAATTACAAGTATTTGTGTTGGATCGGTTGGACGCGCTCACTCGGTTTGGTTTGGTTTGGATTGTATTGGGTTGGATCGGATCGGATTAGCCGCGCTATAGCGTCAGGGGATCAGCTCGGCTCACTGTGGTTTTTGAGGTGTTAGGGTTTGAGTGCTAGGTTGTTTGCTTGATGGATGGTCATTCCTGTGGTGATCTCGGGAGAGTGTCGGAAGTGATATCCGACGGCACCTCATCGGGTAGCGCAGACGGCGGCAAGAGCCTGCCTGAGAAGCATTCTGCGCTGGCTGATGCTACTTCTGGAGTGGCGGCGGAGAATGCCGATAATTTGTCACAAGCTGGGAAGTACATGGATTTCTCCAGTACCACCAGCTTGGGGGTGAAGAAAGGCTTCCAGAAGTGCATGACGTTTCCGCCCTCTAGCGGCGAGGCACAACAGCAGCAGGGTTCATGCTGTGATGCAGATAAGAATCCCAAGGATGTGCCAACCTATGAGCGCTCCGTGTCACTGCCCCCAACTTTGAAGATCATATCTGCTATGAAAGGAAGCCGCCAAAAGAATGGGATGGCTTCATCAACTGAAAGTCGCCACGTCAAATGGGCCCCTGACGTGTATGACCCCCCAGTGACATCTGTATGTCATTCAGTGAATAACAGCTACCAGCGTCGGTCCAAATCCCGGAAGAAGGACAAGAATAAGCAGAAGCAGAAACAAAAGCAAAAGGCGAATTTGATAGGCTCAAGGATGCTGAAACCACAAGTAGTAATTCAGCACCAGACGATCTCAACAAACATGAGACCGATATATTGGATTATGGCATCAGCAGTCAAGACGCCAAATGTGGAAGCAGCTTTTTGCGTGAATCGGCTGCTAAAATGCATTTCTCCACTGCTGAGGCTTCCTGAAAGAAAGGAAAATGAGTCCTGCGGATTCTCCCTTGGTATGTAAATATGATGGATGTGTAGATAAATAAAATCCAGTTTGTTGTTGTGTTTCCTGCTGTGTGAGGCGTTAAGAGAACTTCTGGCGTGCTTTGATTTGGAGCAGTTACCATGACTGTTGGACTGGTTTTTGTATGTATTGATGGACAAAGCTAGTAAGCATTAATCTATGAGCTGCAGTTGTTTTCCTTGATCAATGATTATATATCAGCTGCTGTTGTATTGGTTAT
- >LOC_Os05g02260.4 cDNA AACCGTCAAGAGAGAAGTATTCGGAAAGAAGAGAAGGAAAAAAAGAATTTTTAGAGAGAGGAGGAAAAAAAATATCCCCAATCCCATCATCCCTTCACCCACCCGCACGCGTCTCCTCCGACTCCGATCCGAGCTCCAGATCTGCGGCGCCGGCGACCAACCTCTCCGGCGGCGGGGGCGGCGGCGGAGATCCACGATGCCTTCGTCGGAGCAGGGGGCCTCGCCCCTGCGCCGCCTCCTCCGCGTCGACGCCCTCGTCCTCCCCTCCGCTTGCTCCCACCGCCTTAAGCCTTGGTCTCTCCATCCCCACCTCCTCTCATCCTCCTAACGCCATCCAATCTCTCTTCTCCCCGTCTCTTTCTCCTGCTCCCCGTTGCCCTCCCATTTCTTCCCCTTTTCTTCTCGTAGCTATAGGGTGATACACTTCTCTGATTATTGTTGTTGTTCTTCCCGTGCTGATTTGGATTTAATTACAAGTATTTGTGTTGGATCGGTTGGACGCGCTCACTCGGTTTGGTTTGGTTTGGATTGTATTGGGTTGGATCGGATCGGATTAGCCGCGCTATAGCGTCAGGGGATCAGCTCGGCTCACTGTGGTTTTTGAGGTGTTAGGGTTTGAGTGCTAGGTTGTTTGCTTGATGGATGGTCATTCCTGTGGTGATCTCGGGAGAGTGTCGGAAGTGATATCCGACGGCACCTCATCGGGTAGCGCAGACGGCGGCAAGAGCCTGCCTGAGAAGCATTCTGCGCTGGCTGATGCTACTTCTGGAGTGGCGGCGGAGAATGCCGATAATTTGTCACAAGCTGGGAAGTACATGGATTTCTCCAGTACCACCAGCTTGGGGGTGAAGAAAGGCTTCCAGAAGTGCATGACGTTTCCGCCCTCTAGCGGCGAGGCACAACAGCAGCAGGGTTCATGCTGTGATGCAGATAAGAATCCCAAGGATGTGCCAACCTATGAGCGCTCCGTGTCACTGCCCCCAACTTTGAAGATCATATCTGCTATGAAAGGAAGCCGCCAAAAGAATGGGATGGCTTCATCAACTGAAAGTCGCCACGTCAAATGGGCCCCTGACGTGTATGACCCCCCAGTGACATCTGTATGTCATTCAGTGAATAACAGCTACCAGCGTCGGTCCAAATCCCGGAAGAAGGACAAGAATAAGCAGAAGCAGAAACAAAAGCAAAAGGCGAATTTGATAGGCTCAAGGATGCTGAAACCACAAGTAGTAATTCAGCACCAGACGATCTCAACAAACATGAGACCGATATATTGGATTATGGCATCAGCAGTCAAGACGCCAAATGTGGAAGCAGCTTTTTGCGTGAATCGGCTGCTAAAATGCATTTCTCCACTGCTGAGGCTTCCTGAAAGAAAGGAAAATGAGTCCTGCGGATTCTCCCTTGGTATGTAAATATGATGGATGTGTAGATAAATAAAATCCAGTTTGTTGTTGTGTTTCCTGCTGTGTGAGGCGTTAAGAGAACTTCTGGCGTGCTTTGATTTGGAGCAGTTACCATGACTGTTGGACTGGTTTTTGTATGTATTGATGGACAAAGCTAGTAAGCATTAATCTATGAGCTGCAGTTGTTTTCCTTGATCAATGATTATATATCAGCTGCTGTTGTATTGGTTAT
- >LOC_Os05g02260.2 cDNA AACCGTCAAGAGAGAAGTATTCGGAAAGAAGAGAAGGAAAAAAAGAATTTTTAGAGAGAGGAGGAAAAAAAATATCCCCAATCCCATCATCCCTTCACCCACCCGCACGCGTCTCCTCCGACTCCGATCCGAGCTCCAGATCTGCGGCGCCGGCGACCAACCTCTCCGGCGGCGGGGGCGGCGGCGGAGATCCACGATGCCTTCGTCGGAGCAGGGGGCCTCGCCCCTGCGCCGCCTCCTCCGCGTCGACGCCCTCGTCCTCCCCTCCGCTTGCTCCCACCGCCTTAAGCCTTGGTCTCTCCATCCCCACCTCCTCTCATCCTCCTAACGCCATCCAATCTCTCTTCTCCCCGTCTCTTTCTCCTGCTCCCCGTTGCCCTCCCATTTCTTCCCCTTTTCTTCTCGTAGCTATAGGGTGATACACTTCTCTGATTATTGTTGTTGTTCTTCCCGTGCTGATTTGGATTTAATTACAAGTATTTGTGTTGGATCGGTTGGACGCGCTCACTCGGTTTGGTTTGGTTTGGATTGTATTGGGTTGGATCGGATCGGATTAGCCGCGCTATAGCGTCAGGGGATCAGCTCGGCTCACTGTGGTTTTTGAGGTGTTAGGGTTTGAGTGCTAGGTTGTTTGCTTGATGGATGGTCATTCCTGTGGTGATCTCGGGAGAGTGTCGGAAGTGATATCCGACGGCACCTCATCGGGTAGCGCAGACGGCGGCAAGAGCCTGCCTGAGAAGCATTCTGCGCTGGCTGATGCTACTTCTGGAGTGGCGGCGGAGAATGCCGATAATTTGTCACAAGCTGGGAAGTACATGGATTTCTCCAGTACCACCAGCTTGGGGGTGAAGAAAGGCTTCCAGAAGTGCATGACGTTTCCGCCCTCTAGCGGCGAGGCACAACAGCAGCAGGGTTCATGCTGTGATGCAGATAAGAATCCCAAGGATGTGCCAACCTATGAGCGCTCCGTGTCACTGCCCCCAACTTTGAAGATCATATCTGCTATGAAAGGAAGCCGCCAAAAGAATGGGATGGCTTCATCAACTGAAAGTCGCCACGTCAAATGGGCCCCTGACGTGTATGACCCCCCAGTGACATCTGTATGTCATTCAGTGAATAACAGCTACCAGCGTCGGTCCAAATCCCGGAAGAAGGACAAGAATAAGCAGAAGCAGAAACAAAAGCAAAAGGCGAATTTGATAGGCTCAAGGATGCTGAAACCACAAGTAGTAATTCAGCACCAGACGATCTCAACAAACATGAGACCGATATATTGGATTATGGCATCAGCAGTCAAGACGCCAAATGTGGAAGCAGCTTTTTGCGTGAATCGGCTGCTAAAATGCATTTCTCCACTGCTGAGGCTTCCTGAAAGAAAGGAAAATGAGTCCTGCGGATTCTCCCTTGGTATGTAAATATGATGGATGTGTAGATAAATAAAATCCAGTTTGTTGTTGTGTTTCCTGCTGTGTGAGGCGTTAAGAGAACTTCTGGCGTGCTTTGATTTGGAGCAGTTACCATGACTGTTGGACTGGTTTTTGTATGTATTGATGGACAAAGCTAGTAAGCATTAATCTATGAGCTGCAGTTGTTTTCCTTGATCAATGATTATATATCAGCTGCTGTTGTATTGGTTAT
- >LOC_Os05g02260.1 cDNA AACCGTCAAGAGAGAAGTATTCGGAAAGAAGAGAAGGAAAAAAAGAATTTTTAGAGAGAGGAGGAAAAAAAATATCCCCAATCCCATCATCCCTTCACCCACCCGCACGCGTCTCCTCCGACTCCGATCCGAGCTCCAGATCTGCGGCGCCGGCGACCAACCTCTCCGGCGGCGGGGGCGGCGGCGGAGATCCACGATGCCTTCGTCGGAGCAGGGGGCCTCGCCCCTGCGCCGCCTCCTCCGCGTCGACGCCCTCGTCCTCCCCTCCGCTTGCTCCCACCGCCTTAAGCCTTGGTCTCTCCATCCCCACCTCCTCTCATCCTCCTAACGCCATCCAATCTCTCTTCTCCCCGTCTCTTTCTCCTGCTCCCCGTTGCCCTCCCATTTCTTCCCCTTTTCTTCTCGTAGCTATAGGGTGATACACTTCTCTGATTATTGTTGTTGTTCTTCCCGTGCTGATTTGGATTTAATTACAAGTATTTGTGTTGGATCGGTTGGACGCGCTCACTCGGTTTGGTTTGGTTTGGATTGTATTGGGTTGGATCGGATCGGATTAGCCGCGCTATAGCGTCAGGGGATCAGCTCGGCTCACTGTGGTTTTTGAGGTGTTAGGGTTTGAGTGCTAGGTTGTTTGCTTGATGGATGGTCATTCCTGTGGTGATCTCGGGAGAGTGTCGGAAGTGATATCCGACGGCACCTCATCGGGTAGCGCAGACGGCGGCAAGAGCCTGCCTGAGAAGCATTCTGCGCTGGCTGATGCTACTTCTGGAGTGGCGGCGGAGAATGCCGATAATTTGTCACAAGCTGGGAAGTACATGGATTTCTCCAGTACCACCAGCTTGGGGGTGAAGAAAGGCTTCCAGAAGTGCATGACGTTTCCGCCCTCTAGCGGCGAGGCACAACAGCAGCAGGGTTCATGCTGTGATGCAGATAAGAATCCCAAGGATGTGCCAACCTATGAGCGCTCCGTGTCACTGCCCCCAACTTTGAAGATCATATCTGCTATGAAAGGAAGCCGCCAAAAGAATGGGATGGCTTCATCAACTGAAAGTCGCCACGTCAAATGGGCCCCTGACGTGTATGACCCCCCAGTGACATCTGTATGTCATTCAGTGAATAACAGCTACCAGCGTCGGTCCAAATCCCGGAAGAAGGACAAGAATAAGCAGAAGCAGAAACAAAAGCAAAAGGCGAATTTGATAGGCTCAAGGATGCTGAAACCACAAGTAGTAATTCAGCACCAGACGATCTCAACAAACATGAGACCGATATATTGGATTATGGCATCAGCAGTCAAGACGCCAAATGTGGAAGCAGCTTTTTGCGTGAATCGGCTGCTAAAATGCATTTCTCCACTGCTGAGGCTTCCTGAAAGAAAGGAAAATGAGTCCTGCGGATTCTCCCTTGGTATGTAAATATGATGGATGTGTAGATAAATAAAATCCAGTTTGTTGTTGTGTTTCCTGCTGTGTGAGGCGTTAAGAGAACTTCTGGCGTGCTTTGATTTGGAGCAGTTACCATGACTGTTGGACTGGTTTTTGTATGTATTGATGGACAAAGCTAGTAAGCATTAATCTATGAGCTGCAGTTGTTTTCCTTGATCAATGATTATATATCAGCTGCTGTTGTATTGGTTAT
CDS Sequence
- >LOC_Os05g02260.3 CDS ATGGATGGTCATTCCTGTGGTGATCTCGGGAGAGTGTCGGAAGTGATATCCGACGGCACCTCATCGGGTAGCGCAGACGGCGGCAAGAGCCTGCCTGAGAAGCATTCTGCGCTGGCTGATGCTACTTCTGGAGTGGCGGCGGAGAATGCCGATAATTTGTCACAAGCTGGGAAGTACATGGATTTCTCCAGTACCACCAGCTTGGGGGTGAAGAAAGGCTTCCAGAAGTGCATGACGTTTCCGCCCTCTAGCGGCGAGGCACAACAGCAGCAGGGTTCATGCTGTGATGCAGATAAGAATCCCAAGGATGTGCCAACCTATGAGCGCTCCGTGTCACTGCCCCCAACTTTGAAGATCATATCTGCTATGAAAGGAAGCCGCCAAAAGAATGGGATGGCTTCATCAACTGAAAGTCGCCACGTCAAATGGGCCCCTGACGTGTATGACCCCCCAGTGACATCTGTATGTCATTCAGTGAATAACAGCTACCAGCGTCGGTCCAAATCCCGGAAGAAGGACAAGAATAAGCAGAAGCAGAAACAAAAGCAAAAGGCGAATTTGATAGGCTCAAGGATGCTGAAACCACAAGTAGTAATTCAGCACCAGACGATCTCAACAAACATGAGACCGATATATTGGATTATGGCATCAGCAGTCAAGACGCCAAATGTGGAAGCAGCTTTTTGCGTGAATCGGCTGCTAAAATGCATTTCTCCACTGCTGAGGCTTCCTGAAAGAAAGGAAAATGAGTCCTGCGGATTCTCCCTTGGTATGTAA
- >LOC_Os05g02260.4 CDS ATGGATGGTCATTCCTGTGGTGATCTCGGGAGAGTGTCGGAAGTGATATCCGACGGCACCTCATCGGGTAGCGCAGACGGCGGCAAGAGCCTGCCTGAGAAGCATTCTGCGCTGGCTGATGCTACTTCTGGAGTGGCGGCGGAGAATGCCGATAATTTGTCACAAGCTGGGAAGTACATGGATTTCTCCAGTACCACCAGCTTGGGGGTGAAGAAAGGCTTCCAGAAGTGCATGACGTTTCCGCCCTCTAGCGGCGAGGCACAACAGCAGCAGGGTTCATGCTGTGATGCAGATAAGAATCCCAAGGATGTGCCAACCTATGAGCGCTCCGTGTCACTGCCCCCAACTTTGAAGATCATATCTGCTATGAAAGGAAGCCGCCAAAAGAATGGGATGGCTTCATCAACTGAAAGTCGCCACGTCAAATGGGCCCCTGACGTGTATGACCCCCCAGTGACATCTGTATGTCATTCAGTGAATAACAGCTACCAGCGTCGGTCCAAATCCCGGAAGAAGGACAAGAATAAGCAGAAGCAGAAACAAAAGCAAAAGGCGAATTTGATAGGCTCAAGGATGCTGAAACCACAAGTAGTAATTCAGCACCAGACGATCTCAACAAACATGAGACCGATATATTGGATTATGGCATCAGCAGTCAAGACGCCAAATGTGGAAGCAGCTTTTTGCGTGAATCGGCTGCTAAAATGCATTTCTCCACTGCTGAGGCTTCCTGAAAGAAAGGAAAATGAGTCCTGCGGATTCTCCCTTGGTATGTAA
- >LOC_Os05g02260.2 CDS ATGGATGGTCATTCCTGTGGTGATCTCGGGAGAGTGTCGGAAGTGATATCCGACGGCACCTCATCGGGTAGCGCAGACGGCGGCAAGAGCCTGCCTGAGAAGCATTCTGCGCTGGCTGATGCTACTTCTGGAGTGGCGGCGGAGAATGCCGATAATTTGTCACAAGCTGGGAAGTACATGGATTTCTCCAGTACCACCAGCTTGGGGGTGAAGAAAGGCTTCCAGAAGTGCATGACGTTTCCGCCCTCTAGCGGCGAGGCACAACAGCAGCAGGGTTCATGCTGTGATGCAGATAAGAATCCCAAGGATGTGCCAACCTATGAGCGCTCCGTGTCACTGCCCCCAACTTTGAAGATCATATCTGCTATGAAAGGAAGCCGCCAAAAGAATGGGATGGCTTCATCAACTGAAAGTCGCCACGTCAAATGGGCCCCTGACGTGTATGACCCCCCAGTGACATCTGTATGTCATTCAGTGAATAACAGCTACCAGCGTCGGTCCAAATCCCGGAAGAAGGACAAGAATAAGCAGAAGCAGAAACAAAAGCAAAAGGCGAATTTGATAGGCTCAAGGATGCTGAAACCACAAGTAGTAATTCAGCACCAGACGATCTCAACAAACATGAGACCGATATATTGGATTATGGCATCAGCAGTCAAGACGCCAAATGTGGAAGCAGCTTTTTGCGTGAATCGGCTGCTAAAATGCATTTCTCCACTGCTGAGGCTTCCTGAAAGAAAGGAAAATGAGTCCTGCGGATTCTCCCTTGGTATGTAA
- >LOC_Os05g02260.1 CDS ATGGATGGTCATTCCTGTGGTGATCTCGGGAGAGTGTCGGAAGTGATATCCGACGGCACCTCATCGGGTAGCGCAGACGGCGGCAAGAGCCTGCCTGAGAAGCATTCTGCGCTGGCTGATGCTACTTCTGGAGTGGCGGCGGAGAATGCCGATAATTTGTCACAAGCTGGGAAGTACATGGATTTCTCCAGTACCACCAGCTTGGGGGTGAAGAAAGGCTTCCAGAAGTGCATGACGTTTCCGCCCTCTAGCGGCGAGGCACAACAGCAGCAGGGTTCATGCTGTGATGCAGATAAGAATCCCAAGGATGTGCCAACCTATGAGCGCTCCGTGTCACTGCCCCCAACTTTGAAGATCATATCTGCTATGAAAGGAAGCCGCCAAAAGAATGGGATGGCTTCATCAACTGAAAGTCGCCACGTCAAATGGGCCCCTGACGTGTATGACCCCCCAGTGACATCTGTATGTCATTCAGTGAATAACAGCTACCAGCGTCGGTCCAAATCCCGGAAGAAGGACAAGAATAAGCAGAAGCAGAAACAAAAGCAAAAGGCGAATTTGATAGGCTCAAGGATGCTGAAACCACAAGTAGTAATTCAGCACCAGACGATCTCAACAAACATGAGACCGATATATTGGATTATGGCATCAGCAGTCAAGACGCCAAATGTGGAAGCAGCTTTTTGCGTGAATCGGCTGCTAAAATGCATTTCTCCACTGCTGAGGCTTCCTGAAAGAAAGGAAAATGAGTCCTGCGGATTCTCCCTTGGTATGTAA
Protein Sequence
- >LOC_Os05g02260.3 protein MDGHSCGDLGRVSEVISDGTSSGSADGGKSLPEKHSALADATSGVAAENADNLSQAGKYMDFSSTTSLGVKKGFQKCMTFPPSSGEAQQQQGSCCDADKNPKDVPTYERSVSLPPTLKIISAMKGSRQKNGMASSTESRHVKWAPDVYDPPVTSVCHSVNNSYQRRSKSRKKDKNKQKQKQKQKANLIGSRMLKPQVVIQHQTISTNMRPIYWIMASAVKTPNVEAAFCVNRLLKCISPLLRLPERKENESCGFSLGM*
- >LOC_Os05g02260.4 protein MDGHSCGDLGRVSEVISDGTSSGSADGGKSLPEKHSALADATSGVAAENADNLSQAGKYMDFSSTTSLGVKKGFQKCMTFPPSSGEAQQQQGSCCDADKNPKDVPTYERSVSLPPTLKIISAMKGSRQKNGMASSTESRHVKWAPDVYDPPVTSVCHSVNNSYQRRSKSRKKDKNKQKQKQKQKANLIGSRMLKPQVVIQHQTISTNMRPIYWIMASAVKTPNVEAAFCVNRLLKCISPLLRLPERKENESCGFSLGM*
- >LOC_Os05g02260.2 protein MDGHSCGDLGRVSEVISDGTSSGSADGGKSLPEKHSALADATSGVAAENADNLSQAGKYMDFSSTTSLGVKKGFQKCMTFPPSSGEAQQQQGSCCDADKNPKDVPTYERSVSLPPTLKIISAMKGSRQKNGMASSTESRHVKWAPDVYDPPVTSVCHSVNNSYQRRSKSRKKDKNKQKQKQKQKANLIGSRMLKPQVVIQHQTISTNMRPIYWIMASAVKTPNVEAAFCVNRLLKCISPLLRLPERKENESCGFSLGM*
- >LOC_Os05g02260.1 protein MDGHSCGDLGRVSEVISDGTSSGSADGGKSLPEKHSALADATSGVAAENADNLSQAGKYMDFSSTTSLGVKKGFQKCMTFPPSSGEAQQQQGSCCDADKNPKDVPTYERSVSLPPTLKIISAMKGSRQKNGMASSTESRHVKWAPDVYDPPVTSVCHSVNNSYQRRSKSRKKDKNKQKQKQKQKANLIGSRMLKPQVVIQHQTISTNMRPIYWIMASAVKTPNVEAAFCVNRLLKCISPLLRLPERKENESCGFSLGM*