Gene Details:

  • Gene ID:
  • Gene Symbol: TaGCN2
  • Gene Name: GCN2-type PCR product
  • Genome:
  • Species: Triticum aestivum

Functional Descriptions:

  • Overexpression of GCN2-type protein kinase (TaGCN2) in wheat has profound effects on free amino acid concentration and gene expression.
  • GCN2-type PCR product (TaGCN2) was amplified from wheat (Triticum aestivum) RNA, while a wheat eIF2α homologue was identified in wheat genome data and found to contain a conserved target site for phosphorylation by GCN2.
  • TaGCN2 overexpression in transgenic wheat resulted in significant decreases in total free amino acid concentration in the grain, with free asparagine concentration in particular being much lower than in controls.
  • The study demonstrates that TaGCN2 plays an important role in the regulation of genes encoding enzymes of amino acid biosynthesis in wheat and is the first to implicate GCN2-type protein kinases so clearly in sulphur signalling in any organism.
  • It shows that manipulation of TaGCN2 gene expression could be used to reduce free asparagine accumulation in wheat grain and the risk of acrylamide formation in wheat products.

Literature:

Gene Resources:

Orthologs:

Sequences:

cDNA Sequence
CDS Sequence
Protein Sequence