Gene Details:
Functional Descriptions:
- Subsequent investigations revealed that Pst03724 interferes with the TaCaM3-2B–NAD kinase (NADK) TaNADK2 association and thus inhibits the enzyme activity of TaNADK2 activated by TaCaM3-2B. Knocking down TaNADK2 expression by virus-mediated gene silencing significantly increased fungal growth and development, suggesting a decrease in resistance against Pst infection.
- In conclusion, our findings indicate that Pst effector Pst03724 inhibits the activity of NADK by interfering with the TaCaM3-2B–TaNADK2 association, thereby facilitating Pst infection.
- TaNADK2 was also proved to be a positive factor of wheat resistance.
Function-related keywords:
- growth , development , kinase , resistance , virus
Literature:
- Stripe rust effector Pst03724 modulates host immunity by inhibiting NAD kinase activation by a calmodulin. DOI: 10.1093/plphys/kiae112 ; PMID: 38441329
Related News:
Gene Resources:
- NCBI ID: KP165049
- UniProt accessions:
Orthologs:
Sequences:
cDNA Sequence
CDS Sequence
Protein Sequence