Gene Details:

• Gene ID: Zm00001eb406780
• Gene Symbol: Cr4
• Gene Name: crinkly4
• Genome: Zm-B73-REFERENCE-NAM-5.0
• Species: Zea mays

Functional Descriptions:

• The maize crinkly4 (Cr4) gene encodes a predicted receptor kinase that is required for the normal differentiation of leaf epidermis.
• The Cr4 transcript is most abundant in young developing tissues of the shoot but was not detected in the root.
• Phenotypic analysis of strong mutant alleles indicates that Cr4 functions throughout shoot development to control the differentiation of internal as well as epidermal tissues.
• Epidermal cells appear most sensitive to perturbations in Cr4 signaling because epidermal defects are more pronounced than internal cell defects.
• Thus Cr4 regulates an array of developmental responses including cell proliferation, fate, pattern, and differentiation suggesting a function analogous to growth factor responses in animals.

Function-related keywords:

• leaf ,  root ,  growth ,  development ,  kinase ,  leaf-development ,  shoot ,  root-development ,  root-growth ,  cell-proliferation ,  receptor-kinase ,  epidermis ,  root-epidermal-cells

Literature:

• The maize CR4 receptor-like kinase mediates a growth factor-like differentiation response.   DOI:  10.1002/1526-968x(200007)27:3<104::aid-gene30>3.0.co;2-i ;  PMID:  10951503
• Comparative transcriptomics and network analysis define gene coexpression modules that control maize aleurone development and auxin signaling.   DOI:  10.1002/tpg2.20126 ;  PMID:  34323399

Related News:

Gene Resources:

• NCBI ID: LOC542346
• UniProt accessions: O24585

Sequences: