Gene Details:
- Gene ID: Zm00001eb175190
- Gene Symbol: NOT1
- Gene Name: neighbor of tga1
- Genome: Zm-B73-REFERENCE-NAM-5.0
- Species: Zea mays
Functional Descriptions:
- NOT1 encodes a protein that has 92% amino acid similarity to TGA1 and that is recognized by the TGA1 antibody.
- Genetic mapping and phenotypic data show that tga1, without a contribution from NOT1, controls the difference in covered vs. naked kernels.
- Glume architecture phenotypes of isogenic lines with different genotypes at tga1 and NOT1.
- NOT1 regulates the development of strut roots in the first four to six segments of the stem.
- Glume length was significantly increased when TGA1/NOT1 were knocked down/out.
Function-related keywords:
Literature:
- Evidence That the Origin of Naked Kernels During Maize Domestication Was Caused by a Single Amino Acid Substitution in tga1. DOI: ; PMID: 25943393
- Maize domestication phenotypes reveal strigolactone networks coordinating grain size evolution with kernel-bearing cupule architecture. DOI: ; PMID: 36573016
Related News:
Gene Resources:
- NCBI ID: 103653214
- UniProt accessions: A0A1B1MQB5 , A0A1D6PYB5
Sequences:
cDNA Sequence
- >Zm00001eb175190_T002 TATCTATACACCGCCCGCACCTTCCATTCCTCCTCCTCCGAAGCAGCAGGCAGCAGCTGCATCGCACCTCACACCTCTCGTGTCCATCGATCCAGCCGCCCGCCGCAGCTGCAGCTCTCACTGTTGCTGTGCCACCTCCTCGTCGCCTGTAGTGTCGACAGAGAAACGCCCGCTGAATGAGAGGGAAGGAACGGAAGCTGCAGCGGGCGCGCGAGTGCAAGGACTAGGACTAGCGGTTGCAACGTCGGCGCGCGCGCGCGTGCGGCGTACGTCGGGCATGGATTGGGATCTCAAGGCGGTGGGCGCGTGGGACCTCGCGGAGCTGGAGCAGGACCACGCGGCCGCCACGGCAGCAGCGGGGCCGTCCGAGGGCCACGCCACCGATACTGCCGCGGCGGGCACGGGCACGGGGACGGGGACGGAGAGCCGCCCGCCCGGAGCAGGGGCACCCGCCGAGTGCTCTGTGGACTTGAAGCTGGGCGGGATGGGCGAGTGCGAGCTCGGCGCGGGCGCGGCGACGGCCTGCAGGGAGAGGGAGGCCGCGGCGGGGGCGACGAAGCGGCCGCGCCCCGCCGGGCAGCAGCAGCAGCAGTGCCCGTCGTGCGCGGTGGATGGGTGCAGAGCGGACCTGAGCAAGTGCCGCGACTACCACCGGCGGCACAAGGTGTGCGAGGCGCACTCCAAGACCCCCGTCGTCGTCGTGGCCGGCCGCGAGATGCGCTTCTGCCAGCAGTGCAGCAGACTTCGTAGCTTTCTTTATCCGTATGGAGAACGAAACTGCTGTACAGTATACCATCGTGTGGTCCAAGGTTTGACAGGTCTCACAGTATTTTCCTGTCTCTAAGCGCTGATGGACGTACGATTCCATTTACTTGCGGAGTTCGACGCCGACAAGCGCAGCTGCAGAAAGCGTCTGGACGGCCATAATCGCCGCCGCAGGAAGCCACAGCCAGACACCATGGCTTCTGCTAGCTCTATCACAAGCCAGCAAGGCACACGATTCTCACCATTTGCGCCTCCAAGACTGGAGGCGAGCTGGCCGGGGGTGATGAAAACCGAGGAGAGTCCATATCGCATCACTCACCAAATCCATCTGGGCTCCAGCAGCAGCAGCAGGCAGCAGCATTTCGTGGGAGCCGCCACGTCTGCCTACGCCAAAGAAGGCCCGCGCTTCCCTTTCCTGCAGGAGGGCGAGATAAGCTTCGCCACCGGCGTGGTGTTGGAGCCGCCGGCGGCGGCTCCAGCGTGCCAGCCGCTCCTCAAGTCGGGAGCACCACCACCCGAGAGCAGCAGCGCCGGCGGCGGGAAGATGTTCTCCGATCAGGGGCTGACTCGCGTGCTCGACTCGGACTGTGCTCTCTCTCTTCTGTCAGCGCCGGCCAACTACTCCGGCATCGACGTCAGCAGGATGGTCCGCCCGACTGAACACGTCCCCATGGCCCAGCAGCTCGTGGTCTCGGGCCTGCAGTTCGGCAGCGCGTCGTGGTTCCCGCGCCCCCAGGCTTCCACGGGCGGCTCCTTCGTCTCATCCTGCCCCGCCGTGCAGGTGGAGGGCGAGCAGCAGCTGAACGCCGTGCTGGGCCCCAACGACAGCGAGGTGAGCATGAACTACGGCGGGATGTTCCACGTCGGCGGCGGCAGCGGCGGCGGCGAGGGCTCCTCGGACGGCGGCACCTCGTCGTCGATGCCCTTCTCGTGGCAGTAGTCGTCGTCACTTGTCAGCAGCCGCTGCGTTCTCTCATCTTTCGCGCTTCAGACGATCTGGTAGGGAGATACTGGCTTTAGTGATCACTGATCAGCATTGATCCCCCCCCCCCCCCCCCCACTTTTTGTCGAATCGGCTCTGCTAGCCAGCATTATTGTGGACATTTTTTGAATCGTCTCTAGAATAGTCGCCGATGCGTGCCTTAGCAGCGCACAGACATTGTTAGTTTGGTCGCAACGATCAATGGCATGTTTGCTCACTTTACATTCCTTCTGTTTAGCAAGAGACAACTGCTCTGGTCGGTATTCAGGAATAGATCAAGAGCCATTGCAAAAGGGGTAAAACCTCACGTATAGAACACCTCCAAAAAAAATCATTGACCCAACGTTGTATTGTATCCTAGCCTAGCATCGTGCATCAGAGCAGGGGGATGTTGGATTTCGTGACCACGAGCTTTCAAAGATCGGAGATGCGTTTCCCGCTGATGAAATCCACCACTTTGGTGACTGCCAGCTCCAGTGCCGTCGTCACGGCAATCAGGTTCTGCAGAAACTCCTCATACGTTGGCTTCACCCCATCCACGATATCAGTCACAGCTTTCACAAAGATCGCTGGTGTCGAGAACATGTCAGCGACATATGCTACAGCAG
- >Zm00001eb175190_T003 TATCTATACACCGCCCGCACCTTCCATTCCTCCTCCTCCGAAGCAGCAGGCAGCAGCTGCATCGCACCTCACACCTCTCGTGTCCATCGATCCAGCCGCCCGCCGCAGCTGCAGCTCTCACTGTTGCTGTGCCACCTCCTCGTCGCCTGTAGTGTCGACAGAGAAACGCCCGCTGAATGAGAGGGAAGGAACGGAAGCTGCAGCGGGCGCGCGAGTGCAAGGACTAGGACTAGCGGTTGCAACGTCGGCGCGCGCGCGCGTGCGGCGTACGTCGGGCATGGATTGGGATCTCAAGGCGGTGGGCGCGTGGGACCTCGCGGAGCTGGAGCAGGACCACGCGGCCGCCACGGCAGCAGCGGGGCCGTCCGAGGGCCACGCCACCGATACTGCCGCGGCGGGCACGGGCACGGGGACGGGGACGGAGAGCCGCCCGCCCGGAGCAGGGGCACCCGCCGAGTGCTCTGTGGACTTGAAGCTGGGCGGGATGGGCGAGTGCGAGCTCGGCGCGGGCGCGGCGACGGCCTGCAGGGAGAGGGAGGCCGCGGCGGGGGCGACGAAGCGGCCGCGCCCCGCCGGGCAGCAGCAGCAGCAGTGCCCGTCGTGCGCGGTGGATGGGTGCAGAGCGGACCTGAGCAAGTGCCGCGACTACCACCGGCGGCACAAGGTGTGCGAGGCGCACTCCAAGACCCCCGTCGTCGTCGTGGCCGGCCGCGAGATGCGCTTCTGCCAGCAGTGCAGCAGACTTCGTAGCTTTCTTTATCCGTATGGAGAACGAAACTGCTGTACAGTATACCATCGTGTGGTCCAAGGTTTGACAGGTCTCACAGTATTTTCCTGTCTCTAAGCGCTGATGGACGTACGATTCCATTTACTTGCGGAGTTCGACGCCGACAAGCGCAGCTGCAGAAAGCGTCTGGACGGCCATAATCGCCGCCGCAGGAAGCCACAGCCAGACACCATGGCTTCTGCTAGCTCTATCACAAGCCAGCAAGGCACACGATTCTCACCATTTGCGCCTCCAAGACTGGAGGCGAGCTGGCCGGGGGTGATGAAAACCGAGGAGAGTCCATATCGCATCACTCACCAAATCCATCTGGGCTCCAGCAGCAGCAGCAGGCAGCAGCATTTCGTGGGAGCCGCCACGTCTGCCTACGCCAAAGAAGGCCCGCGCTTCCCTTTCCTGCAGGAGGGCGAGATAAGCTTCGCCACCGGCGTGGTGTTGGAGCCGCCGGCGGCGGCTCCAGCGTGCCAGCCGCTCCTCAAGTCGGGAGCACCACCACCCGAGAGCAGCAGCGCCGGCGGCGGGAAGATGTTCTCCGATCAGGGGCTGACTCGCGTGCTCGACTCGGACTGTGCTCTCTCTCTTCTGTCAGCGCCGGCCAACTACTCCGGCATCGACGTCAGCAGGATGGTCCGCCCGACTGAACACGTCCCCATGGCCCAGCAGCTCGTGGTCTCGGGCCTGCAGTTCGGCAGCGCGTCGTGGTTCCCGCGCCCCCAGGCTTCCACGGGCGGCTCCTTCGTCTCATCCTGCCCCGCCGTGCAGGTGGAGGGCGAGCAGCAGCTGAACGCCGTGCTGGGCCCCAACGACAGCGAGGTGAGCATGAACTACGGCGGGATGTTCCACGTCGGCGGCGGCAGCGGCGGCGGCGAGGGCTCCTCGGACGGCGGCACCTCGTCGTCGATGCCCTTCTCGTGGCAGTAGTCGTCGTCACTTGTCAGCAGCCGCTGCGTTCTCTCATCTTTCGCGCTTCAGACGATCTGGTAGGGAGATACTGGCTTTAGTGATCACTGATCAGCATTGATCCCCCCCCCCCCCCCCCCACTTTTTGTCGAATCGGCTCTGCTAGCCAGCATTATTGTGGACATTTTTTGAATCGTCTCTAGAATAGTCGCCGATGCGTGCCTTAGCAGCGCACAGACATTGTTAGTTTGGTCGCAACGATCAATGGCATGTTTGCTCACTTTACATTCCTTCTGTTTAGCAAGAGACAACTGCTCTGGTCGGTATTCAGGAATAGATCAAGAGCCATTGCAAAAGGGGTAAAACCTCACGTATAGAACACCTCCAAAAAAAATCATTGACCCAACGTTGTATTGTATCCTAGCCTAGCATCGTGCATCAGAGCAGGGGGATGTTGGATTTCGTGACCACGAGCTTTCAAAGATCGGAGATGCGTTTCCCGCTGATGAAATCCACCACTTTGGTGACTGCCAGCTCCAGTGCCGTCGTCACGGCAATCAGGTTCTGCAGAAACTCCTCATACGTTGGCTTCACCCCATCCACGATATCAGTCACAGCTTTCACAAAGATCGCTGGTGTCGAGAACATGTCAGCGACATATGCTACAGCAG
- >Zm00001eb175190_T001 TATCTATACACCGCCCGCACCTTCCATTCCTCCTCCTCCGAAGCAGCAGGCAGCAGCTGCATCGCACCTCACACCTCTCGTGTCCATCGATCCAGCCGCCCGCCGCAGCTGCAGCTCTCACTGTTGCTGTGCCACCTCCTCGTCGCCTGTAGTGTCGACAGAGAAACGCCCGCTGAATGAGAGGGAAGGAACGGAAGCTGCAGCGGGCGCGCGAGTGCAAGGACTAGGACTAGCGGTTGCAACGTCGGCGCGCGCGCGCGTGCGGCGTACGTCGGGCATGGATTGGGATCTCAAGGCGGTGGGCGCGTGGGACCTCGCGGAGCTGGAGCAGGACCACGCGGCCGCCACGGCAGCAGCGGGGCCGTCCGAGGGCCACGCCACCGATACTGCCGCGGCGGGCACGGGCACGGGGACGGGGACGGAGAGCCGCCCGCCCGGAGCAGGGGCACCCGCCGAGTGCTCTGTGGACTTGAAGCTGGGCGGGATGGGCGAGTGCGAGCTCGGCGCGGGCGCGGCGACGGCCTGCAGGGAGAGGGAGGCCGCGGCGGGGGCGACGAAGCGGCCGCGCCCCGCCGGGCAGCAGCAGCAGCAGTGCCCGTCGTGCGCGGTGGATGGGTGCAGAGCGGACCTGAGCAAGTGCCGCGACTACCACCGGCGGCACAAGGTGTGCGAGGCGCACTCCAAGACCCCCGTCGTCGTCGTGGCCGGCCGCGAGATGCGCTTCTGCCAGCAGTGCAGCAGACTTCGTAGCTTTCTTTATCCGTATGGAGAACGAAACTGCTGTACAGTATACCATCGTGTGGTCCAAGGTTTGACAGGTCTCACAGTATTTTCCTGTCTCTAAGCGCTGATGGACGTACGATTCCATTTACTTGCGGAGTTCGACGCCGACAAGCGCAGCTGCAGAAAGCGTCTGGACGGCCATAATCGCCGCCGCAGGAAGCCACAGCCAGACACCATGGCTTCTGCTAGCTCTATCACAAGCCAGCAAGGCACACGATTCTCACCATTTGCGCCTCCAAGACTGGAGGCGAGCTGGCCGGGGGTGATGAAAACCGAGGAGAGTCCATATCGCATCACTCACCAAATCCATCTGGGCTCCAGCAGCAGCAGCAGGCAGCAGCATTTCGTGGGAGCCGCCACGTCTGCCTACGCCAAAGAAGGCCCGCGCTTCCCTTTCCTGCAGGAGGGCGAGATAAGCTTCGCCACCGGCGTGGTGTTGGAGCCGCCGGCGGCGGCTCCAGCGTGCCAGCCGCTCCTCAAGTCGGGAGCACCACCACCCGAGAGCAGCAGCGCCGGCGGCGGGAAGATGTTCTCCGATCAGGGGCTGACTCGCGTGCTCGACTCGGACTGTGCTCTCTCTCTTCTGTCAGCGCCGGCCAACTACTCCGGCATCGACGTCAGCAGGATGGTCCGCCCGACTGAACACGTCCCCATGGCCCAGCAGCTCGTGGTCTCGGGCCTGCAGTTCGGCAGCGCGTCGTGGTTCCCGCGCCCCCAGGCTTCCACGGGCGGCTCCTTCGTCTCATCCTGCCCCGCCGTGCAGGTGGAGGGCGAGCAGCAGCTGAACGCCGTGCTGGGCCCCAACGACAGCGAGGTGAGCATGAACTACGGCGGGATGTTCCACGTCGGCGGCGGCAGCGGCGGCGGCGAGGGCTCCTCGGACGGCGGCACCTCGTCGTCGATGCCCTTCTCGTGGCAGTAGTCGTCGTCACTTGTCAGCAGCCGCTGCGTTCTCTCATCTTTCGCGCTTCAGACGATCTGGTAGGGAGATACTGGCTTTAGTGATCACTGATCAGCATTGATCCCCCCCCCCCCCCCCCCACTTTTTGTCGAATCGGCTCTGCTAGCCAGCATTATTGTGGACATTTTTTGAATCGTCTCTAGAATAGTCGCCGATGCGTGCCTTAGCAGCGCACAGACATTGTTAGTTTGGTCGCAACGATCAATGGCATGTTTGCTCACTTTACATTCCTTCTGTTTAGCAAGAGACAACTGCTCTGGTCGGTATTCAGGAATAGATCAAGAGCCATTGCAAAAGGGGTAAAACCTCACGTATAGAACACCTCCAAAAAAAATCATTGACCCAACGTTGTATTGTATCCTAGCCTAGCATCGTGCATCAGAGCAGGGGGATGTTGGATTTCGTGACCACGAGCTTTCAAAGATCGGAGATGCGTTTCCCGCTGATGAAATCCACCACTTTGGTGACTGCCAGCTCCAGTGCCGTCGTCACGGCAATCAGGTTCTGCAGAAACTCCTCATACGTTGGCTTCACCCCATCCACGATATCAGTCACAGCTTTCACAAAGATCGCTGGTGTCGAGAACATGTCAGCGACATATGCTACAGCAG
CDS Sequence
- >Zm00001eb175190_T002 ATGGACGTACGATTCCATTTACTTGCGGAGTTCGACGCCGACAAGCGCAGCTGCAGAAAGCGTCTGGACGGCCATAATCGCCGCCGCAGGAAGCCACAGCCAGACACCATGGCTTCTGCTAGCTCTATCACAAGCCAGCAAGGCACACGATTCTCACCATTTGCGCCTCCAAGACTGGAGGCGAGCTGGCCGGGGGTGATGAAAACCGAGGAGAGTCCATATCGCATCACTCACCAAATCCATCTGGGCTCCAGCAGCAGCAGCAGGCAGCAGCATTTCGTGGGAGCCGCCACGTCTGCCTACGCCAAAGAAGGCCCGCGCTTCCCTTTCCTGCAGGAGGGCGAGATAAGCTTCGCCACCGGCGTGGTGTTGGAGCCGCCGGCGGCGGCTCCAGCGTGCCAGCCGCTCCTCAAGTCGGGAGCACCACCACCCGAGAGCAGCAGCGCCGGCGGCGGGAAGATGTTCTCCGATCAGGGGCTGACTCGCGTGCTCGACTCGGACTGTGCTCTCTCTCTTCTGTCAGCGCCGGCCAACTACTCCGGCATCGACGTCAGCAGGATGGTCCGCCCGACTGAACACGTCCCCATGGCCCAGCAGCTCGTGGTCTCGGGCCTGCAGTTCGGCAGCGCGTCGTGGTTCCCGCGCCCCCAGGCTTCCACGGGCGGCTCCTTCGTCTCATCCTGCCCCGCCGTGCAGGTGGAGGGCGAGCAGCAGCTGAACGCCGTGCTGGGCCCCAACGACAGCGAGGTGAGCATGAACTACGGCGGGATGTTCCACGTCGGCGGCGGCAGCGGCGGCGGCGAGGGCTCCTCGGACGGCGGCACCTCGTCGTCGATGCCCTTCTCGTGGCAGTAG
- >Zm00001eb175190_T003 ATGGACGTACGATTCCATTTACTTGCGGAGTTCGACGCCGACAAGCGCAGCTGCAGAAAGCGTCTGGACGGCCATAATCGCCGCCGCAGGAAGCCACAGCCAGACACCATGGCTTCTGCTAGCTCTATCACAAGCCAGCAAGGCACACGATTCTCACCATTTGCGCCTCCAAGACTGGAGGCGAGCTGGCCGGGGGTGATGAAAACCGAGGAGAGTCCATATCGCATCACTCACCAAATCCATCTGGGCTCCAGCAGCAGCAGCAGGCAGCAGCATTTCGTGGGAGCCGCCACGTCTGCCTACGCCAAAGAAGGCCCGCGCTTCCCTTTCCTGCAGGAGGGCGAGATAAGCTTCGCCACCGGCGTGGTGTTGGAGCCGCCGGCGGCGGCTCCAGCGTGCCAGCCGCTCCTCAAGTCGGGAGCACCACCACCCGAGAGCAGCAGCGCCGGCGGCGGGAAGATGTTCTCCGATCAGGGGCTGACTCGCGTGCTCGACTCGGACTGTGCTCTCTCTCTTCTGTCAGCGCCGGCCAACTACTCCGGCATCGACGTCAGCAGGATGGTCCGCCCGACTGAACACGTCCCCATGGCCCAGCAGCTCGTGGTCTCGGGCCTGCAGTTCGGCAGCGCGTCGTGGTTCCCGCGCCCCCAGGCTTCCACGGGCGGCTCCTTCGTCTCATCCTGCCCCGCCGTGCAGGTGGAGGGCGAGCAGCAGCTGAACGCCGTGCTGGGCCCCAACGACAGCGAGGTGAGCATGAACTACGGCGGGATGTTCCACGTCGGCGGCGGCAGCGGCGGCGGCGAGGGCTCCTCGGACGGCGGCACCTCGTCGTCGATGCCCTTCTCGTGGCAGTAG
- >Zm00001eb175190_T001 ATGGACGTACGATTCCATTTACTTGCGGAGTTCGACGCCGACAAGCGCAGCTGCAGAAAGCGTCTGGACGGCCATAATCGCCGCCGCAGGAAGCCACAGCCAGACACCATGGCTTCTGCTAGCTCTATCACAAGCCAGCAAGGCACACGATTCTCACCATTTGCGCCTCCAAGACTGGAGGCGAGCTGGCCGGGGGTGATGAAAACCGAGGAGAGTCCATATCGCATCACTCACCAAATCCATCTGGGCTCCAGCAGCAGCAGCAGGCAGCAGCATTTCGTGGGAGCCGCCACGTCTGCCTACGCCAAAGAAGGCCCGCGCTTCCCTTTCCTGCAGGAGGGCGAGATAAGCTTCGCCACCGGCGTGGTGTTGGAGCCGCCGGCGGCGGCTCCAGCGTGCCAGCCGCTCCTCAAGTCGGGAGCACCACCACCCGAGAGCAGCAGCGCCGGCGGCGGGAAGATGTTCTCCGATCAGGGGCTGACTCGCGTGCTCGACTCGGACTGTGCTCTCTCTCTTCTGTCAGCGCCGGCCAACTACTCCGGCATCGACGTCAGCAGGATGGTCCGCCCGACTGAACACGTCCCCATGGCCCAGCAGCTCGTGGTCTCGGGCCTGCAGTTCGGCAGCGCGTCGTGGTTCCCGCGCCCCCAGGCTTCCACGGGCGGCTCCTTCGTCTCATCCTGCCCCGCCGTGCAGGTGGAGGGCGAGCAGCAGCTGAACGCCGTGCTGGGCCCCAACGACAGCGAGGTGAGCATGAACTACGGCGGGATGTTCCACGTCGGCGGCGGCAGCGGCGGCGGCGAGGGCTCCTCGGACGGCGGCACCTCGTCGTCGATGCCCTTCTCGTGGCAGTAG
Protein Sequence
- >Zm00001eb175190_P002 MDVRFHLLAEFDADKRSCRKRLDGHNRRRRKPQPDTMASASSITSQQGTRFSPFAPPRLEASWPGVMKTEESPYRITHQIHLGSSSSSRQQHFVGAATSAYAKEGPRFPFLQEGEISFATGVVLEPPAAAPACQPLLKSGAPPPESSSAGGGKMFSDQGLTRVLDSDCALSLLSAPANYSGIDVSRMVRPTEHVPMAQQLVVSGLQFGSASWFPRPQASTGGSFVSSCPAVQVEGEQQLNAVLGPNDSEVSMNYGGMFHVGGGSGGGEGSSDGGTSSSMPFSWQ
- >Zm00001eb175190_P003 MDVRFHLLAEFDADKRSCRKRLDGHNRRRRKPQPDTMASASSITSQQGTRFSPFAPPRLEASWPGVMKTEESPYRITHQIHLGSSSSSRQQHFVGAATSAYAKEGPRFPFLQEGEISFATGVVLEPPAAAPACQPLLKSGAPPPESSSAGGGKMFSDQGLTRVLDSDCALSLLSAPANYSGIDVSRMVRPTEHVPMAQQLVVSGLQFGSASWFPRPQASTGGSFVSSCPAVQVEGEQQLNAVLGPNDSEVSMNYGGMFHVGGGSGGGEGSSDGGTSSSMPFSWQ
- >Zm00001eb175190_P001 MDVRFHLLAEFDADKRSCRKRLDGHNRRRRKPQPDTMASASSITSQQGTRFSPFAPPRLEASWPGVMKTEESPYRITHQIHLGSSSSSRQQHFVGAATSAYAKEGPRFPFLQEGEISFATGVVLEPPAAAPACQPLLKSGAPPPESSSAGGGKMFSDQGLTRVLDSDCALSLLSAPANYSGIDVSRMVRPTEHVPMAQQLVVSGLQFGSASWFPRPQASTGGSFVSSCPAVQVEGEQQLNAVLGPNDSEVSMNYGGMFHVGGGSGGGEGSSDGGTSSSMPFSWQ