Gene Details:

• Gene ID: Zm00001eb349250
• Gene Symbol: ZmGDIα-hel ZmGDIα RabGDIα gdi1
• Gene Name: guanosine nucleotide diphosphate dissociation inhibitor1
• Genome: Zm-B73-REFERENCE-NAM-5.0
• Species: Zea mays

Functional Descriptions:

• Rab GDP dissociation inhibitor alpha (RabGDIα) is the host susceptibility factor for RBSDV.
• A helitron-induced RabGDIα variant causes quantitative recessive resistance to maize rough dwarf disease.
• The resultant splicing variant RabGDIα-hel has difficulty being recruited by P7-1, thus leading to quantitative recessive resistance to MRDD.
• ZmGDIα-hel, a causal gene for qMrdd1, which confers passive resistance to MRDD caused by RBSDV.
• ZmGDIα-hel, which reduces the MRDD disease severity index by ~30%.
• Naturally occurring ZmGDIα-hel allele reduces MRDD severity.
• Targeted generation of Null Mutants in ZmGDIα confers resistance against maize rough dwarf disease without agronomic penalty.
• The natural variant with an alternative exon 10 caused by a helitron transposon insertion, designated ZmGDIα-hel, weakened the interaction between the RBSDV P7-1 protein and the encoded ZmGDIα-hel protein, leading to quantitative resistance in maize plants.

Function-related keywords:

• resistance ,  disease ,  disease-resistance ,  dwarf

Literature:

• A helitron-induced RabGDIα variant causes quantitative recessive resistance to maize rough dwarf disease.   DOI:  10.1038/s41467-020-14372-3 ;  PMID:  31980630
• Genetic dissection of crown root traits and their relationships with aboveground agronomic traits in maize.   DOI:  10.1016/j.jia.2023.04.022
• Targeted generation of Null Mutants in ZmGDIα confers resistance against maize rough dwarf disease without agronomic penalty.   DOI:  10.1111/pbi.13793 ;  PMID:  35178853

Related News:

• Nature Commun | 中国农业大学徐明良课题组首次发现玉米粗缩病抗病基因

Gene Resources:

• NCBI ID: LOC100284832
• UniProt accessions: B4G082

Sequences: