Gene Details:

• Gene ID: GRMZM2G164467
• Gene Symbol: ZmLAC3
• Gene Name: laccase6
• Genome: B73_RefGen_v3
• Species: Zea mays

Functional Descriptions:

• Consistent with results obtained with ZmmiR528 TM transgenic maize and mir528a/b loss-of-function mutants, transgenic maize overexpressing ZmLAC3 displayed early CS formation under different N conditions.
• Under field conditions, K, Ca, Mn, Cu, Mg, and Zn concentrations were greater in the ear leaf of ZmLAC3-overexpressing transgenic maize than in the wild type.
• Nitrogen supply affects ion homeostasis by modifying root Casparian strip formation through the miR528-LAC3 module in maize.
• Overexpression of ZmLAC3 promotes CS formation under different N conditions.
• Effects of ZmLAC3 overexpression on Casparian strip formation in roots, and mineral element profiles in ear leaves of field-grown maize.
• The crystal structure of ZmLac3 revealed a compact and deep substrate-binding pocket, and the binding modes of sinapyl alcohol (SinA) and coniferyl alcohol (ConA) were solved.
• These results indicate that, by regulating the expression of ZmLAC3 and ZmLAC5, ZmmiR528 affects maize lodging resistance under N-luxury conditions.

Function-related keywords:

• nitrogen ,  leaf ,  root ,  homeostasis ,  casparian-strip

Literature:

• Nitrogen supply affects ion homeostasis by modifying root Casparian strip formation through the miR528-LAC3 module in maize.   DOI:  10.1016/j.xplc.2023.100553 ;  PMID:  36681862
• WOOLLY, interacting with MYB transcription factor MYB31, regulates cuticular wax biosynthesis by modulating CER6 expression in tomato.   DOI:  10.1111/tpj.14733 ;  PMID:  32129912
• microRNA528 affects lodging resistance of maize by regulating lignin biosynthesis under nitrogen-luxury conditions.   DOI:  10.1016/j.molp.2018.03.013 ;  PMID:  29597009

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Gene Resources:

• NCBI ID: 732787
• UniProt accessions: C0P789

Sequences: